Evidence map›Paper›PMID 30134552›Full record

ArticleInternational journal of molecular sciences2018

Involvement of Connexin Hemichannels in the Inflammatory Response of Chronic Diseases.

Juan C Sáez, Colin Green

Abstract readEditorial
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Mechanisms Underlying Connexin Hemichannel Activation in Disease.International journal of molecular sciences · 2021
    Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Juan C SáezDepartamento de Fisiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Alameda 340, 8331150 Santiago, Chile. jsaez@bio.puc.cl.
Colin GreenDepartment of Ophthalmology, New Zealand National Eye Centre, University of Auckland, Auckland 1142, New Zealand. c.green@auckland.ac.nz.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last decade it has become evident that under normal conditions connexin hemichannels are either not expressed (e.g., skeletal muscle) or are expressed in very low numbers with low open probability in various mammalian tissues (e.g., liver and central nervous system (CNS)).[...].

Indexed as

Adenosine TriphosphateAnimalsAnti-Inflammatory AgentsBiological TransportCalciumCations, DivalentCell CommunicationConnexin 43ConnexinsDiazoxideGap JunctionsGene Expression RegulationHumansInflammationKATP ChannelsMachine LearningAdenosine TriphosphateAnti-Inflammatory AgentsCalciumCations, DivalentConnexin 43ConnexinsDiazoxideKATP ChannelsPeptide FragmentsTAT-Gap19 peptide

Identifiers

PMID30134552
PMCPMC6164707

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.