SynthesisInternational journal of molecular sciences2018
rs495139 in the TYMS-ENOSF1 Region and Risk of Ovarian Carcinoma of Mucinous Histology.
Open access · goldAbstract readMeta-Analysis
In one paragraph
Synthesis in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 4 citations in OpenAlex.
- Integrated bioinformatics analysis for the screening of hub genes and therapeutic drugs in ovarian cancer.Journal of ovarian research · 2020Article
- Association Between Genetic Polymorphisms InOncoTargets and therapy · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
129 authors at 20 institutions in 11 countries.
Linda E KelemenHollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA. Kelemen@musc.edu.ORCID 0000-0003-4362-9784
Madalene EarpDepartment of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN 55905, USA. madalene.earp@ucalgary.ca.
Brooke L FridleyDepartment of Biostatistics and Bioinformatics, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612 USA. brooke.fridley@moffitt.org.
Georgia Chenevix-TrenchDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia. georgia.trench@qimr.edu.au.
Australian Ovarian Cancer Study GroupDepartment of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia.
Peter A FaschingDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, 91054 Erlangen, Germany. peter.fasching@uk-erlangen.de.
Matthias W BeckmannDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, 91054 Erlangen, Germany. fk-direktion@uk-erlangen.de.
Arif B EkiciInstitute of Human Genetics, Friedrich-Alexander-University Erlangen-Nuremberg, Comprehensive Cancer Center Erlangen Nuremberg, Erlangen 91054, Germany. arif.ekici@uk-erlangen.de.
Alexander HeinDepartment of Gynecology and Obstetrics, University Hospital Erlangen, Friedrich-Alexander University Erlangen-Nuremberg, Comprehensive Cancer Center, 91054 Erlangen, Germany. alexander.hein@uk-erlangen.de.ORCID 0000-0003-2601-3398
Diether LambrechtsVesalius Research Center, University of Leuven, Leuven 3001, Belgium. diether.lambrechts@vib-kuleuven.be.
Sandrina LambrechtsDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven 3000, Belgium. sandrina.lambrechts@mumc.nl.
Els Van NieuwenhuysenDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven 3000, Belgium. els.vannieuwenhuysen@uzleuven.be.
Ignace VergoteDivision of Gynecologic Oncology, Department of Obstetrics and Gynaecology and Leuven Cancer Institute, University Hospitals Leuven, Leuven 3000, Belgium. ignace.vergote@uzleuven.be.
Mary Anne RossingProgram in Epidemiology, Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. mrossing@fhcrc.org.
Jennifer A DohertyHuntsman Cancer Institute, Department of Population Health Sciences, University of Utah, Salt Lake City, UT 84112, USA. jennifer.doherty@hci.utah.edu.
Jenny Chang-ClaudeDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. j.chang-claude@dkfz-heidelberg.de.
Sabine BehrensDivision of Cancer Epidemiology, German Cancer Research Center (DKFZ), Heidelberg 69120, Germany. s.behrens@dkfz.de.ORCID 0000-0002-9714-104X
Kirsten B MoysichDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. moysich@roswellpark.org.
Rikki CanniotoDepartment of Cancer Prevention and Control, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. rikki.cannioto@roswellpark.org.
Shashikant LeleDepartment of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. shashi.lele@roswellpark.org.
Kunle OdunsiDepartment of Gynecological Oncology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA. kunle.odunsi@roswellpark.org.
Marc T GoodmanDepartment of Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. marc.goodman@cshs.org.
Yurii B ShvetsovCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA. yshvetso@cc.hawaii.edu.
Pamela J ThompsonDepartment of Cancer Prevention and Control, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. pamela.thompson@cshs.org.
Lynne R WilkensCancer Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI 96813, USA. lynne@cc.hawaii.edu.
Thilo DörkGynaecology Research Unit, Hannover Medical School, Hannover 30625, Germany. doerk.thilo@mh-hannover.de.
Natalia AntonenkovaByelorussian Institute for Oncology and Medical Radiology Aleksandrov N.N., Minsk 223040, Belarus. antonenkova.natalia.omd@tut.by.
Natalia BogdanovaGynaecology Research Unit, Hannover Medical School, Hannover 30625, Germany. bogdanova.natalia@mh-hannover.de.
Peter HillemannsClinics of Obstetrics and Gynaecology, Hannover Medical School, Hannover 30625, Germany. hillemanns.peter@mh-hannover.de.ORCID 0000-0001-9829-3531
Ingo B RunnebaumDepartment of Gynecology, Jena University Hospital-Friedrich Schiller University, Jena 07743, Germany. ingo.runnebaum@med.uni-jena.de.
Andreas du BoisDepartment of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte (KEM), Essen 45136, Germany. prof.dubois@googlemail.com.
Philipp HarterDepartment of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte (KEM), Essen 45136, Germany. p.harter@gmx.de.
Florian HeitzDepartment of Gynecology and Gynecologic Oncology, Kliniken Essen-Mitte (KEM), Essen 45136, Germany. florian.heitz@gmx.net.
Ira SchwaabPraxis für Humangenetik, Wiesbaden 65187, Germany. iraschwaab@gmx.de.
Ralf ButzowDepartment of Pathology, University of Helsinki and Helsinki University Hospital, Helsinki 00290, Finland. ralf.butzow@hus.fi.
Liisa M PelttariDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki 00290, Finland. liisa.pelttari@helsinki.fi.
Heli NevanlinnaDepartment of Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki 00290, Finland. heli.nevanlinna@hus.fi.ORCID 0000-0002-0916-2976
Francesmary ModugnoDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. fm@cs.cmu.edu.
Robert P EdwardsDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. redwards@mail.magee.edu.
Joseph L KelleyDivision of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA. jkelley@mail.magee.edu.
Roberta B NessSchool of Public Health, The University of Texas Health Science Center at Houston (UTHealth), Houston, TX 77030, USA. roberta.b.ness@uth.tmc.edu.
Beth Y KarlanWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. beth.karlan@cshs.org.
Jenny LesterWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. jenny.lester@cshs.org.
Sandra OrsulicWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. sandra.orsulic@cshs.org.
Christine WalshWomen's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. christine.walsh@cshs.org.
Susanne K KjaerDepartment of Gynaecology, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, Denmark. susanne@cancer.dk.ORCID 0000-0002-8347-1398
Allan JensenDepartment of Virus, Lifestyle and Genes, Danish Cancer Society Research Centre, DK-2100 Copenhagen, Denmark. allan@cancer.dk.ORCID 0000-0001-8124-4880
Julie M CunninghamDepartment of Laboratory Medicine and Pathology, Division of Experimental Pathology, Mayo Clinic, Rochester, MN 55905, USA. cunningham.julie@mayo.edu.ORCID 0000-0002-8159-3025
Robert A VierkantDepartment of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA. vierkant.robert@mayo.edu.ORCID 0000-0001-6242-5221
Graham G GilesCentre for Epidemiology and Biostatistics, University of Melbourne, VIC 3010, Australia. graham.giles@cancervic.org.au.
Fiona BruinsmaCancer Epidemiology and Intelligence Division, Cancer Council Victoria, Melbourne, VIC 3004, Australia. fiona.bruinsma@cancervic.org.au.
Melissa C SoutheyDepartment of Pathology, University of Melbourne, Melbourne, VIC 3010, Australia. msouthey@unimelb.edu.au.
Michelle A T HildebrandtDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. mhildebr@mdanderson.org.
Dong LiangCollege of Pharmacy and Health Sciences, Texas Southern University, Houston, TX 77004, USA. liang_dx@tsu.edu.
Karen LuDepartment of Gynecologic Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. khlu@mdanderson.org.
Xifeng WuDepartment of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. xwu@mdanderson.org.
Thomas A SellersDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. thomas.sellers@moffitt.org.
Douglas A LevineLaura and Isaac Perlmutter Cancer Center, New York University Langone Health, New York, NY 10016, USA. Douglas.Levine@nyumc.org.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA 22908, USA. jms2yf@virginia.edu.
Edwin S IversenDepartment of Statistical Science, Duke University, Durham, NC 27708, USA. iversen@stat.duke.edu.
Kathryn L TerryDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. kterry@partners.org.
Daniel W CramerDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. dcramer@partners.org.
Shelley S TworogerDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. shelley.tworoger@moffitt.org.
Elizabeth M PooleChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. nhlip@channing.harvard.edu.
Elisa V BanderaCancer Prevention and Control Program, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA. banderel@cinj.rutgers.edu.
Sara H OlsonMemorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, NY 10065, USA. olsons@mskcc.org.
Irene OrlowMemorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, NY 10065, USA. orlowi@mskcc.org.
Liv Cecilie Vestrheim ThomsenDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway. Liv.Vestrheim@uib.no.
Line BjorgeDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway. line.bjorge@uib.no.ORCID 0000-0002-0240-2770
Camilla KrakstadDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway. camilla.krakstad@k2.uib.no.
Ingvild L TangenDepartment of Gynecology and Obstetrics, Haukeland University Hospital, Bergen 5021, Norway. ingvild.tangen@k2.uib.no.
Lambertus A KiemeneyRadboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen 6525 EZ, The Netherlands. bart.kiemeney@radboudumc.nl.
Katja K H AbenRadboud University Medical Centre, Radboud Institute for Health Sciences, Nijmegen 6525 EZ, The Netherlands. k.aben@iknl.nl.
Leon F A G MassugerRadboud University Medical Centre, Department of Obstetrics and Gynecology, Nijmegen 6525 GA, The Netherlands. leon.massuger@radboudumc.nl.
Anne M van AltenaRadboud University Medical Centre, Department of Obstetrics and Gynecology, Nijmegen 6525 GA, The Netherlands. anne.vanaltena@radboudumc.nl.
Tanja PejovicDepartment of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA. pejovict@ohsu.edu.
Yukie BeanDepartment of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA. beany@ohsu.edu.
Melissa KellarDepartment of Obstetrics and Gynecology, Oregon Health and Science University, Portland, OR 97239, USA. kellar@ohsu.edu.
Linda S CookDivision of Epidemiology, Biostatistics and Preventive Medicine, Department of Internal Medicine, University of New Mexico, Albuquerque, NM 87131, USA. lcook@salud.unm.edu.
Nhu D LeCancer Control Research, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada. nle@bccrc.ca.
Angela Brooks-WilsonCanada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC V5Z 1L3, Canada. abrooks-wilson@bcgsc.ca.
Jacek GronwaldInternational Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 71-252, Poland. jgron@sci.pam.szczecin.pl.ORCID 0000-0002-3643-2871
Cezary CybulskiInternational Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 71-252, Poland. cezarycy@sci.pam.szczecin.pl.
Anna JakubowskaInternational Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 71-252, Poland. aniaj@sci.pam.szczecin.pl.
Jan LubińskiInternational Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical University, Szczecin 71-252, Poland. lubinski@pum.edu.pl.
Nicolas WentzensenDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA. wentzenn@mail.nih.gov.
Louise A BrintonDivision of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD 20892, USA. brintonl@mail.nih.gov.ORCID 0000-0003-3853-8562
Jolanta LissowskaDepartment of Cancer Epidemiology and Prevention, M. Sklodowska-Curie Institute-Oncology Center, Warsaw 02-034, Poland. lissowsj@coi.waw.pl.
Estrid HogdallDepartment of Virus, Lifestyle and Genes, Danish Cancer Society Research Centre, DK-2100 Copenhagen, Denmark. hogdall@dadlnet.dk.
Svend Aage EngelholmDepartment of Radiation Oncology, Rigshospitalet, University of Copenhagen, Copenhagen DK-2100, Denmark. svend.aage.engelholm@rh.regionh.dk.
Claus HogdallDepartment of Gynaecology, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, Denmark. claus.hogdall@regionh.dk.
Lene LundvallDepartment of Gynaecology, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, Denmark. lene.lundvall@regionh.dk.
Lotte NedergaardDepartment of Pathology, Rigshospitalet, University of Copenhagen, Copenhagen DK-2100, Denmark. lotte.thomsen.01@regionh.dk.
Paul D P PharoahThe Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge CB1 8RN, UK. pp10001@medschl.cam.ac.uk.ORCID 0000-0001-8494-732X
Ed DicksThe Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK. emd43@medschl.cam.ac.uk.
Honglin SongThe Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK. hs310@medschl.cam.ac.uk.
Jonathan P TyrerThe Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge CB1 8RN, UK. jpt34@medschl.cam.ac.uk.ORCID 0000-0003-3724-4757
Iain McNeishOvarian Cancer Action Research Centre, Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK. i.mcneish@imperial.ac.uk.ORCID 0000-0002-9387-7586
Nadeem SiddiquiDepartment of Gynaecological Oncology, Glasgow Royal Infirmary, Glasgow G4 0SF, UK. nadeem.siddiqui@ggc.scot.nhs.uk.
Karen CartyCancer Research UK Clinical Trials Unit, The Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, UK. karen.carty@glasgow.ac.uk.
Rosalind GlasspoolCancer Research UK Clinical Trials Unit, The Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, UK. ros.glasspool@ggc.scot.nhs.uk.
James PaulCancer Research UK Clinical Trials Unit, The Beatson West of Scotland Cancer Centre, Glasgow G12 0YN, UK. james.paul@glasgow.ac.uk.
Ian G CampbellDepartment of Pathology, University of Melbourne, Melbourne, VIC 3010, Australia. ian.campbell@petermac.org.
Diana EcclesFaculty of Medicine, University of Southampton, Southampton SO17 1BJ, UK. d.m.eccles@soton.ac.uk.ORCID 0000-0002-9935-3169
Alice S WhittemoreDepartment of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA. alicesw@stanford.edu.
Valerie McGuireDepartment of Health Research and Policy, Stanford University School of Medicine, Stanford, CA 94305, USA. vmcguire@stanford.edu.
Joseph H RothsteinDepartment of Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. joseph.rothstein@mssm.edu.
Weiva SiehDepartment of Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. weiva.sieh@mssm.edu.
Steven A NarodWomen's College Research Institute, University of Toronto, Toronto, ON M5S 1A8, Canada. steven.narod@wchospital.ca.
Catherine M PhelanDepartment of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA. ocacdata@duke.edu.
John R McLaughlinPublic Health Ontario, Samuel Lunenfeld Research Institute, Toronto, ON M5T 3L9, Canada. jmclaugh@lunenfeld.ca.
Harvey A RischDepartment of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT 06510, USA. harvey.risch@yale.edu.
Hoda Anton-CulverDepartment of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, CA 92617, USA. hantoncu@uci.edu.
Argyrios ZiogasDepartment of Epidemiology, Genetic Epidemiology Research Institute, School of Medicine, University of California Irvine, Irvine, CA 92617, USA. aziogas@uci.edu.
Usha MenonMRC Clinical Trials at UCL, Institute of Clinical Trials & Methodology, Population Health Sciences, University College London, London, WC1V 6LJ, UK. u.menon@ucl.ac.uk.ORCID 0000-0003-3708-1732
Simon A GaytherDepartment of Biomedical Sciences and Center for Cancer Prevention and Translational Genomics, Samuel Oschin Comprensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. simon.gayther@cshs.org.
Aleksandra Gentry-MaharajMRC Clinical Trials at UCL, Institute of Clinical Trials & Methodology, Population Health Sciences, University College London, London, WC1V 6LJ, UK. a.gentry-maharaj@ucl.ac.uk.
Susan J RamusSchool of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Sydney, NSW 2052, Australia. s.ramus@unsw.edu.au.ORCID 0000-0003-0005-7798
Anna H WuDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA. anna.wu@med.usc.edu.
Celeste Leigh PearceDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA. lpearce@umich.edu.
Alice W LeeDepartment of Public Health, California State University, Fullerton, CA 92831, USA. alicelee@fullerton.edu.
Malcolm C PikeMemorial Sloan Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, NY 10065, USA. pikem@mskcc.org.
Jolanta KupryjanczykDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, Warsaw 02-034, Poland. jkupry@coi.waw.pl.
Agnieszka PodgorskaDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, Warsaw 02-034, Poland. ag.podgorski@yahoo.de.
Joanna Plisiecka-HalasaDepartment of Pathology and Laboratory Diagnostics, Maria Sklodowska-Curie Institute-Oncology Center, Warsaw 02-034, Poland. jopliha@coi.waw.pl.
Wlodzimierz SawickiDepartment of Obstetrics, Gynecology and Oncology, Second Faculty of Medicine, Medical University of Warsaw, Mazovian Bródno Hospital, Warsaw 03-242, Poland. saw55@wp.pl.
Ellen L GoodeDepartment of Health Sciences Research, Division of Epidemiology, Mayo Clinic, Rochester, MN 55905, USA. egoode@mayo.edu.
Andrew BerchuckDepartment of Obstetrics and Gynecology, Duke University Medical Center, Durham, NC 27710, USA. andrew.berchuck@duke.edu.
Ovarian Cancer Association Consortium
University of Copenhagen · DKCedars-Sinai Medical Center · USRadboud University Nijmegen · NLThe University of Melbourne · AUThe University of Texas MD Anderson Cancer Center · USUniversity of Southern California · USBrigham and Women's Hospital · USHelios Dr. Horst Schmidt Kliniken Wiesbaden · DEMedizinische Hochschule Hannover · DERoswell Park Comprehensive Cancer Center · USUniversity of Cambridge · GBUniversity of Hawaiʻi at Mānoa · USUniversity of Helsinki · FIBeatson West of Scotland Cancer Centre · GBHaukeland University Hospital · NOInternational Hereditary Cancer Center · PLKU Leuven · BENational Cancer Institute · USOregon Health & Science University · USUniversitätsklinikum Erlangen · DE
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4MUCLA Clinical Translational Science InstituteUL1TR001881 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ARLEEN F. BROWN, ARASH NAEIM · 2016 to 2026
$118.1MUniversity of Hawaii Cancer Center CCSGP30CA071789 · NCI · UNIVERSITY OF HAWAII AT MANOA · PI GERTRAUD MASKARINEC · 1996 to 2026
$56.2MUse of microfluidic tumor cultures to enable clinical trials of therapies for ovarian cancerP50CA136393 · NCI · MAYO CLINIC ROCHESTER · PI ELLEN L. GOODE · 2009 to 2026
$37.0MRPCI-UPCI Ovarian Cancer SPOREP50CA159981 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI MOYSICH, KIRSTEN B., ODUNSI, KUNLE · 2013 to 2025
$19.6MTraining Grant in Genomic Analysis and InterpretationT32ES013678 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GAUDERMAN, WILLIAM JAMES, MCCONNELL, ROB S · 2006 to 2023
$5.6MCancer Research UK 15973Cancer Research UK C490/A10119Cancer Research UK C490/A10124Cancer Research UK C490/A16561Cancer Research UK C490/A6187Cancer Research UK C536/A13086Cancer Research UK C536/A6689CIHR MOP-86727Medical Research Council G0501974Medical Research Council G0601891NCATS NIH HHS UL1 TR001881NCI NIH HHS K07-CA080668NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA071789NCI NIH HHS P50 CA136393NCI NIH HHS P50 CA159981NCI NIH HHS R01-CA067262NIEHS NIH HHS T32ES013678
Abstract
Thymidylate synthase (TYMS) is a crucial enzyme for DNA synthesis. TYMS expression is regulated by its antisense mRNA, ENOSF1. Disrupted regulation may promote uncontrolled DNA synthesis and tumor growth. We sought to replicate our previously reported association between rs495139 in the
Indexed as
Gene Expression Regulation, NeoplasticPolymorphism, Single NucleotideAdenocarcinoma, MucinousCase-Control StudiesFemaleGenetic Association StudiesHumansHydro-LyasesLogistic ModelsMiddle AgedOdds RatioOvarian NeoplasmsProteinsQuantitative Trait LociRiskRNA, AntisenseENOSF1 protein, humanHydro-LyasesProteinsRNA, AntisenseThymidylate SynthaseTYMS protein, humanconsortiaenolase superfamily member 1expression quantitative trait locusgeneticsgynecologyovarian neoplasmssingle-nucleotide polymorphismthymidylate synthase
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.