Evidence map›Paper›PMID 30142914›Full record

ArticleMolecules (Basel, Switzerland)2018

JNK Inactivation Induces Polyploidy and Drug-Resistance in Coronarin D-Treated Osteosarcoma Cells.

Chang-Te Hsu, Yi-Fu Huang, Chen-Pu Hsieh, Chia-Chieh Wu, Tai-Shan Shen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Global modulation of gene expression and transcriptome size in aneuploid combinations of maize.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Antitumoral Properties of Natural Products.Molecules (Basel, Switzerland) · 2020
    Article
  8. Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα.Molecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chang-Te HsuDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua 50006, Taiwan. 169485@cch.org.tw.
Yi-Fu HuangOrthopedics & Sports Medicine Laboratory, Changhua Christian Hospital, Changhua 50006, Taiwan. 181064@cch.org.tw.
Chen-Pu HsiehDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua 50006, Taiwan. 51114@cch.org.tw.
Chia-Chieh WuDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua 50006, Taiwan. 50560@cch.org.tw.
Tai-Shan ShenDepartment of Orthopedic Surgery, Changhua Christian Hospital, Changhua 50006, Taiwan. 162509@cch.org.tw.
Changhua Christian Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inhibition of proliferating cells is a critical strategy for cancer therapy. In this study, we demonstrated that coronarin D, a natural component extracted from the rhizomes of

Indexed as

ApoptosisCaspase 3Cell Cycle CheckpointsCell LineCell Line, TumorCyclin B1DiterpenesFlow CytometryHumansImmunoblottingJNK Mitogen-Activated Protein KinasesMitosisOsteosarcomaPolyploidySignal TransductionCASP3 protein, humanCaspase 3coronarin DCyclin B1DiterpenesJNK Mitogen-Activated Protein Kinasescoronarin DJNKosteosarcoma

Identifiers

PMID30142914
PMCPMC6225306
OpenAlexW2888447907

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.