Evidence map›Paper›PMID 30142967›Full record

ArticleInternational journal of molecular sciences2018

The Effect of Ca

Jianing Li, Zhiyi Yu, Jianjun Xu, Rui Feng, Qinghua Gao, Tomasz Boczek, Junyan Liu, Zhi Li, Qianhui Wang, Ming Lei and 6 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Calmodulin Interactions with Voltage-Gated Sodium Channels.International journal of molecular sciences · 2021
    Review
  2. Properties of Calmodulin Binding to NaNeurochemical research · 2021
    Article
  3. Article
  4. [Effect of calmodulin and its mutants on binding to NaZhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 3 countries.

Jianing LiDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. Ariene77687@outlook.com.
Zhiyi YuDepartment of Neurobiology, Harvard Medical School, Boston, MA 02115, USA. zhiyi7566@live.cn.
Jianjun XuDepartment of Physiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan. jjxuk@m3.kufm.kagoshima-u.ac.jp.
Rui FengDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. fengrui527@163.com.
Qinghua GaoDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. rwygao@m.kufm.kagoshima-u.ac.jp.
Tomasz BoczekDepartment of Ophthalmology, Stanford University School of Medicine, Palo Alto, CA 94305, USA. tomasz.boczek@umed.lodz.pl.ORCID 0000-0002-7654-9011
Junyan LiuDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. m18602444860_1@163.com.
Zhi LiDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. lizhi0824@live.com.
Qianhui WangDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. WQH91225@163.com.
Ming LeiDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. leiming@swmu.edu.cn.
Jian GongDepartment of Clinical Pharmacy, School of Life Science and Biopharmaceutics, Shenyang Pharmaceutical University, Shenyang 110016, China. fanxing1230@163.com.
Huiyuan HuDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. hyhu@cmu.edu.cn.
Etsuko MinobeDepartment of Physiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan. mimiben@m3.kufm.kagoshima-u.ac.jp.ORCID 0000-0003-1351-0440
Hong-Long JiDepartment of Cellular and Molecular Biology, University of Texas Health Science Center at Tyler, Tyler, TX 75708, USA. james.ji@uthct.edu.ORCID 0000-0002-3228-7144
Masaki KameyamaDepartment of Physiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima 890-8544, Japan. kame@m.kufm.kagoshima-u.ac.jp.ORCID 0000-0002-0083-7295
Feng GuoDepartment of Pharmaceutical Toxicology, School of Pharmacy, China Medical University, Shenyang 110122, China. blueforest611@hotmail.com.
China Medical University · CNKagoshima University · JPHarvard University · USShenyang Pharmaceutical University · CNStanford University · USThe University of Texas Health Science Center at Tyler · US

Funding

NOVEL PARACRINE MECHANISMS FOR CELL-BASED THERAPY OF INJURED LUNGSR01HL134828 · NHLBI · UNIVERSITY OF TEXAS HLTH CTR AT TYLER · PI JI, HONG-LONG · 2017 to 2025
$3.4M
NHLBI NIH HHS R01 HL134828
6 · The paper itself

Abstract

Calmodulin (CaM) is well known as an activator of calcium/calmodulin-dependent protein kinase II (CaMKII). Voltage-gated sodium channels (VGSCs) are basic signaling molecules in excitable cells and are crucial molecular targets for nervous system agents. However, the way in which Ca

Indexed as

Amino Acid SequenceBinding SitesCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinCloning, MolecularCrystallography, X-RayEscherichia coliGene ExpressionGenetic VectorsGlutathione TransferaseHEK293 CellsHumansKineticsMolecular Docking SimulationMutationCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2CalmodulinGlutathione TransferaseNAV1.1 Voltage-Gated Sodium ChannelRecombinant Fusion ProteinsSCN1A protein, humanCa2+CaMCaMKIIIQ domainNaV1.1

Identifiers

PMID30142967
PMCPMC6165294
OpenAlexW2888220182

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.