Evidence map›Paper›PMID 30149197›Full record

ReviewBrain research bulletin2019

Brain banking in low and middle-income countries: Raison D'être for the Ibadan Brain Ageing, Dementia And Neurodegeneration (IBADAN) Brain Bank Project.

Rufus O Akinyemi, Ayodeji Salami, Joshua Akinyemi, Akin Ojagbemi, Funmi Olopade, Motunrayo Coker, Temitope Farombi, Michael Nweke, Oyedunni Arulogun, Ayodele Jegede and 3 more

Abstract readReview
In one paragraph

Review in Brain research bulletin, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Gaps in biomedical research in frontotemporal dementia: A call for diversity and disparities focused research.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Review
  9. Review
  10. Review
  11. Article
  12. The African Dementia Consortium.The Lancet. Neurology · 2023
    Article
  13. Dementia in Africa: Current evidence, knowledge gaps, and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022
    Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Rufus O AkinyemiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria. Electronic address: roakinyemi@com.ui.edu.ng.
Ayodeji SalamiDepartment of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Joshua AkinyemiDepartment of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Akin OjagbemiDepartment of Psychiatry, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Funmi OlopadeDepartment of Anatomy, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Motunrayo CokerInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Temitope FarombiChief Tony Anenih Geriatric Centre, University College Hospital, Ibadan, Nigeria.
Michael NwekeDepartment of Pathology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Oyedunni ArulogunDepartment of Health Education and Promotion, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Ayodele JegedeDepartment of Sociology, Faculty of the Social Sciences, University of Ibadan, Ibadan, Nigeria.
Mayowa OwolabiDepartment of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.
Rajesh N KalariaInstitute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom.
Adesola OgunniyiInstitute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Ibadan, Nigeria; Department of Medicine, College of Medicine, University of Ibadan, Ibadan, Nigeria.

Funding

Stroke Investigative Research & Educational Network (SIREN)U54HG007479 · NHGRI · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2013 to 2017
$4.2M
Systematic Investigation of Blacks with Stroke - Genomics (SIBS-Genomics) StudyR01NS107900 · NINDS · COLLEGE OF MEDICINE, UNIVERSITY OF IBADAN · PI OVBIAGELE, BRUCE, OWOLABI, MAYOWA OJO · 2018 to 2021
$1.8M
Medical Research Council G0400074Medical Research Council G0502157Medical Research Council G0900652Medical Research Council G1100540NHGRI NIH HHS U54 HG007479NINDS NIH HHS R01 NS107900
6 · The paper itself

Abstract

Brain banks are biorepositories of central nervous system (CNS) tissue including fixed and frozen whole brains, brain biopsies and spinal cord, as well as body fluids comprising the cerebrospinal fluid (CSF) and blood stored for research purposes. Though several independent brain banks exist in high income countries, only five low- and middle - income countries (LMIC) have brain banks. The African continent is yet to establish a formalized brain bank despite its huge human genomic diversity, ageing of her populations with concomitant increases in ageing - associated brain disorders and differential phenotypic expression and outcomes of brain disorders. Cellular and molecular clinicopathological studies are vital to shaping our understanding of the interaction between racial (genetic) and geographical (environmental) factors in the natural history and mechanisms of disease, and unravelling frameworks of diagnostic biomarkers, and new therapeutic and preventative interventions. The Ibadan Brain Ageing, Dementia And Neurodegeneration (IBADAN) Brain Bank, the first organized brain tissue biorepository in sub - Saharan Africa, is set up to accrue, process and store unique brain tissues for future research into a broad spectrum of neurological and psychiatric disorders. The potential unique discoveries and research breakthroughs will benefit people of African ancestry and other ancestral populations.

Indexed as

Africa South of the SaharaBiological Specimen BanksBrainBrain DiseasesCentral Nervous SystemDementiaDeveloping CountriesHumansNigeriaAfricaBrain BankingBrain DisordersLMICNigeria

Identifiers

PMID30149197
PMCPMC8285571

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.