Evidence map›Paper›PMID 30155445›Full record

ArticleFrontiers in cellular and infection microbiology2018

Is IL-1β Further Evidence for the Role of

Ondrej Slaby, Andrew McDowell, Holger Brüggemann, Assaf Raz, Sibel Demir-Deviren, Tony Freemont, Peter Lambert, Manu N Capoor

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03866447 (Vitamin D and Its Topical Analogues), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03866447 phase4unknown statusnot on this mapstarted 2019, after this paper: background citation

Vitamin D and Its Topical Analogues: A Possible Role in the Pathogenesis and Treatment of Acne Vulgaris

TypeinterventionalSponsorAssiut UniversityRan2019 to 2021Enrolled80ConditionsAcne VulgarisArmsVitamin D analog, Adapalene
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. WouldJournal of personalized medicine · 2023
    Article
  5. Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Ondrej SlabyCentral European Institute of Technology, Masaryk University, Brno, Czechia.
Andrew McDowellNorthern Ireland Centre for Stratified Medicine, School of Biomedical Sciences, Ulster University, Londonderry, United Kingdom.
Holger BrüggemannDepartment of Biomedicine, Aarhus University, Aarhus, Denmark.
Assaf RazLaboratory of Bacterial Pathogenesis and Immunology, Rockefeller University, New York, NY, United States.
Sibel Demir-DevirenSpine Center, UCSF Medical Center, San Francisco, CA, United States.
Tony FreemontDivision of Cell Matrix Biology and Regenerative Medicine, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, United Kingdom.
Peter LambertSchool of Life and Health Sciences, Aston University, Birmingham, United Kingdom.
Manu N CapoorCentral European Institute of Technology, Masaryk University, Brno, Czechia.
Rockefeller University · USAarhus University · DKAston University · GBCentral European Institute of Technology – Masaryk University · CZUniversity of California San Francisco Medical Center · USUniversity of Manchester · GBUniversity of Ulster · GB

Funding

Medical Research Council MR/N00583X/1
6 · The paper itself

Abstract

The pathogenesis of degenerative disc disease is a complex and multifactorial process in which genetics, mechanical trauma, altered loading and nutrition present significant etiological factors. Infection of the intervertebral disc with the anaerobic bacterium

Indexed as

DiscitisGram-Positive Bacterial InfectionsHumansInterleukin-1betaIntervertebral Disc DegenerationModels, BiologicalPropionibacterium acnesInterleukin-1betaacne vulgarisdegenerative disc diseaseinterleukin-1 betanerve growth factor (NGF)Propionibacterium acnes

Identifiers

PMID30155445
PMCPMC6103242
OpenAlexW2887840450

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.