Evidence map›Paper›PMID 30166337›Full record

ArticleEMBO reports2018

Kit ligand has a critical role in mouse yolk sac and aorta-gonad-mesonephros hematopoiesis.

Emanuele Azzoni, Vincent Frontera, Kathleen E McGrath, Joe Harman, Joana Carrelha, Claus Nerlov, James Palis, Sten Eirik W Jacobsen, Marella Ftr de Bruijn

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Transition of signal requirement in hematopoietic stem cell development from hemogenic endothelial cells.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. PDGFRβCell reports · 2022
    Article
  16. Review
  17. Article
  18. Article
  19. Mds1Cell reports · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Emanuele AzzoniMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK emanuele.azzoni@imm.ox.ac.uk marella.debruijn@imm.ox.ac.uk.ORCID 0000-0002-4572-5692
Vincent FronteraMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Kathleen E McGrathDepartment of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, NY, USA.
Joe HarmanMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.ORCID 0000-0003-3668-1859
Joana CarrelhaMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Claus NerlovMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
James PalisDepartment of Pediatrics, Center for Pediatric Biomedical Research, University of Rochester Medical Center, Rochester, NY, USA.
Sten Eirik W JacobsenMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.
Marella Ftr de BruijnMRC Molecular Hematology Unit, MRC Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK emanuele.azzoni@imm.ox.ac.uk marella.debruijn@imm.ox.ac.uk.ORCID 0000-0002-4934-4125
University of Oxford · GBUniversity of Rochester Medical Center · USKarolinska University Hospital · SE

Funding

Ontogeny of erythroid lineage differentiationR01DK071116 · NIDDK · UNIVERSITY OF ROCHESTER · PI PALIS, JAMES · 2006 to 2010
$2.2M
Erythroid precursor self-renewalR01HL130670 · NHLBI · UNIVERSITY OF ROCHESTER · PI PALIS, JAMES · 2015 to 2018
$1.8M
Embryonic hematopoietic stem cell origin and ontogenyR01DK060403 · NIDDK · UNIVERSITY OF ROCHESTER · PI PALIS, JAMES · 2001 to 2004
$1.7M
Medical Research Council G0501838Medical Research Council G0701761Medical Research Council G0801073Medical Research Council G0900892Medical Research Council G0902418Medical Research Council MC_PC_12020Medical Research Council MC_UU_00016/2Medical Research Council MC_UU_00016/5Medical Research Council MC_UU_00016/7Medical Research Council MC_UU_12009/2Medical Research Council MC_UU_12009/5Medical Research Council MC_UU_12009/7Medical Research Council MC_UU_12010Medical Research Council MC_UU_12025Medical Research Council MR/K015777X/1Medical Research Council MR/M00919X/1NHLBI NIH HHS R01 HL130670NIDDK NIH HHS R01 DK060403NIDDK NIH HHS R01 DK071116
6 · The paper itself

Abstract

Few studies report on the

Indexed as

AnimalsAortaCell LineageCell ProliferationEmbryonic DevelopmentEndothelial CellsErythropoiesisGene Expression Regulation, DevelopmentalGonadsHematopoiesisHematopoietic Stem CellsMesonephrosMiceMice, TransgenicStem Cell FactorStem Cell NicheStem Cell FactorAGMembryohematopoiesisKit ligandniche

Identifiers

PMID30166337
PMCPMC6172468
OpenAlexW2888773054

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.