ArticleMolecular and cellular biology1985
Phosphatidylinositol kinase activities in normal and Rous sarcoma virus-transformed cells.
Article in Molecular and cellular biology, 1985. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 53 citations in OpenAlex.
- Cellular processes of v-Src transformation revealed by gene profiling of primary cells--implications for human cancer.BMC cancer · 2010Article
- Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice.Aging cell · 2007Article
- Modulating effects of the extracellular sequence of the human insulinlike growth factor I receptor on its transforming and tumorigenic potential.Journal of virology · 1993Article
- Induction of neurite outgrowth by v-src mimics critical aspects of nerve growth factor-induced differentiation.Molecular and cellular biology · 1991Article
- Deletion or substitution within the alpha platelet-derived growth factor receptor kinase insert domain: effects on functional coupling with intracellular signaling pathways.Molecular and cellular biology · 1991Article
- Phosphatidylinositol metabolism in cells transformed by polyomavirus middle T antigen.Journal of virology · 1990Article
- Phosphatidylinositol kinase activity associates with viral p60src protein.Molecular and cellular biology · 1989Article
- Phosphorylation of diacylglycerol kinase in vitro by protein kinase C.The Biochemical journal · 1989Article
- Dissociation of inositol trisphosphate from diacylglycerol production in Rous sarcoma virus-transformed fibroblasts.The Journal of cell biology · 1989Article
- Occurrence of immunoreactive 80 kDa and non-immunoreactive diacylglycerol kinases in different pig tissues.The Biochemical journal · 1988Article
- Phosphatidylinositol kinase is activated in membranes derived from cells treated with epidermal growth factor.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
- Evidence for two distinct phosphatidylinositol kinases in fibroblasts. Implications for cellular regulation.The Biochemical journal · 1987Article
- Constitutive expression of a gene encoding a polypeptide homologous to biologically active human platelet protein in Rous sarcoma virus-transformed fibroblasts.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
- A protein kinase antigenically related to pp60v-src possibly involved in yeast cell cycle control: positive in vivo regulation by sterol.Proceedings of the National Academy of Sciences of the United States of America · 1987Article
- Calcium, cyclic AMP and protein kinase C--partners in mitogenesis.Cancer metastasis reviews · 1987Review
- Retrovirus shuttle vector for study of kinase activities of pp60c-src synthesized in vitro and overproduced in vivo.Molecular and cellular biology · 1986Article
- Phosphatidylinositol metabolism and polyoma-mediated transformation.Proceedings of the National Academy of Sciences of the United States of America · 1986Article
- Downregulation of cell-to-cell communication by the viral src gene is blocked by TMB-8 and recovery of communication is blocked by vanadate.The Journal of membrane biology · 1986Article
- Diacylglycerol downregulates junctional membrane permeability. TMB-8 blocks this effect.The Journal of membrane biology · 1985Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The phosphatidylinositol (PI), phosphatidylinositol 4-phosphate (PIP), and diacylglycerol kinase activities in the plasma membrane-rich fraction of chicken embryo fibroblasts infected with a temperature-sensitive mutant of Rous sarcoma virus increased when the cells were shifted from the nonpermissive temperature, 41 degrees C, to the permissive temperature, 35 degrees C. Temperature shift from 35 to 41 degrees C decreased the lipid kinase activities in the membrane vesicles. These changes accompanied the changes observed in pp60v-src protein kinase activity. Thermal inactivation at 41 degrees C did not appreciably reduce PI and PIP kinase activities in membrane vesicles prepared from uninfected or Rous sarcoma virus-transformed cells, whereas pp60v-src protein kinase activity in the membrane vesicles was rapidly inactivated under the same conditions. These data suggest that pp60v-src may indirectly enhance PI and PIP phosphorylation but not directly contribute to this pathway.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.