Evidence map›Paper›PMID 30199756›Full record

ReviewCell calcium2018

CRAC channel-based optogenetics.

Nhung Thi Nguyen, Guolin Ma, Eena Lin, Brendan D'Souza, Ji Jing, Lian He, Yun Huang, Yubin Zhou

Abstract readReview
In one paragraph

Review in Cell calcium, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. STIM1 and lipid interactions at ER-PM contact sites.American journal of physiology. Cell physiology · 2025
    Review
  4. Article
  5. ORAI CaBiomolecules · 2024
    Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Optogenetic Control of Non-Apoptotic Cell Death.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Article
  15. Article
  16. Article
  17. Mechanism of STIM activation.Current opinion in physiology · 2020
    Article
  18. Optogenetic approaches to control CaCurrent opinion in physiology · 2020
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Nhung Thi NguyenCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Guolin MaCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Eena LinCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Brendan D'SouzaCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Ji JingCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Lian HeCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA.
Yun HuangCenter for Epigenetics and Disease Prevention, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M University, College Station, TX 77843, USA.
Yubin ZhouCenter for Translational Cancer Research, Institute of Biosciences and Technology, College of Medicine, Texas A&M University, Houston, TX 77030, USA; Department of Medical Physiology, College of Medicine, Texas A&M University, Temple, TX 76504, USA. Electronic address: yubinzhou@tamu.edu.
Texas A&M University · USTexas A&M University System · US

Funding

MOLECULAR CONTROL OF CALCIUM INFLUX AT THE ER-PLASMA MEMBRANE JUNCTIONSR01GM112003 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI ZHOU, YUBIN · 2014 to 2022
$2.7M
TET-mediated epigenetic regulation in cardiac development.R01HL134780 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HUANG, YUN · 2018 to 2022
$1.9M
Role of TET dioxygenase associated immune mechanisms in cardiac injury and repairR01HL146852 · NHLBI · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HUANG, YUN · 2019 to 2022
$1.7M
Optogenetic toolkit for remote control of voltage-gated calcium channelsR21GM126532 · NIGMS · TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR · PI HAN, GANG, ZHOU, YUBIN · 2018 to 2019
$443k
NHLBI NIH HHS R01 HL134780NHLBI NIH HHS R01 HL146852NIGMS NIH HHS R01 GM112003NIGMS NIH HHS R21 GM126532
6 · The paper itself

Abstract

Store-operated Ca²

Indexed as

OptogeneticsAnimalsCalciumCalcium Release Activated Calcium ChannelsHumansModels, BiologicalProtein DomainsProtein MultimerizationCalciumCalcium Release Activated Calcium ChannelsCRISPR/Cas9Ion channelMembrane contact sitesOptogeneticsORAIStromal interaction molecule

Identifiers

PMID30199756
PMCPMC6176914
OpenAlexW2891654822

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.