Evidence map›Paper›PMID 30200193›Full record

Trial reportNutrients2018

Favorable Effects of a Ketogenic Diet on Physical Function, Perceived Energy, and Food Cravings in Women with Ovarian or Endometrial Cancer: A Randomized, Controlled Trial.

Caroline W Cohen, Kevin R Fontaine, Rebecca C Arend, Taraneh Soleymani, Barbara A Gower

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 8 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 8 syntheses or guidelines pooled it, 120 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Altered Food Behavior and Cancer: A Systematic Review of the Literature.International journal of environmental research and public health · 2022
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Review
  12. Review
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Review
  20. Charting cancer's course: revealing the role of diet, exercise, and the microbiome in cancer evolution and immunotherapy response.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Caroline W CohenDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. cwyoder@uab.edu.
Kevin R FontaineDepartment of Health Behavior, University of Alabama at Birmingham, Birmingham, AL 35294, USA. kfontai1@uab.edu.ORCID 0000-0002-2807-6440
Rebecca C ArendDepartment of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. rarend@uabmc.edu.
Taraneh SoleymaniDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. tsoleymani@hotmail.com.
Barbara A GowerDepartment of Nutrition Sciences, University of Alabama at Birmingham, Birmingham, AL 35294, USA. bgower@uab.edu.
University of Alabama at Birmingham · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Omer Jamy · 1985 to 2026
$165.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
American Institute for Cancer Research NANCI NIH HHS P30 CA013148NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

Ketogenic diets (KDs) are gaining attention as a potential adjuvant therapy for cancer, but data are limited for KDs' effects on quality of life. We hypothesized that the KD would (1) improve mental and physical function, including energy levels, (2) reduce hunger, and (3) diminish sweet and starchy food cravings in women with ovarian or endometrial cancer. Participants were randomized to a KD (70:25:5 energy from fat, protein, and carbohydrate) or the American Cancer Society diet (ACS: high-fiber, lower-fat). Questionnaires were administered at baseline and after 12 weeks on the assigned diet to assess changes in mental and physical health, perceived energy, appetite, and food cravings. We assessed both between-group differences and within-group changes using ANCOVA and paired

Indexed as

AppetiteAdultAgedCravingDietary FiberDiet, Fat-RestrictedDiet, KetogenicEndometrial NeoplasmsEnergy IntakeExerciseFemaleHumansHungerMiddle AgedOvarian NeoplasmsPerceptionDietary Fiberendometrial cancerfatiguefood cravingsketogenic dietmental functionovarian cancerphysical functionquality of life

Identifiers

PMID30200193
PMCPMC6163837
OpenAlexW2888805411

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.