Evidence map›Paper›PMID 30210552›Full record

ReviewStem cells international2018

Mesenchymal Stromal/Stem Cells in Regenerative Medicine and Tissue Engineering.

Ross E B Fitzsimmons, Matthew S Mazurek, Agnes Soos, Craig A Simmons

Registry-linked trialAbstract readReview
In one paragraph

Review in Stem cells international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06662604 (Evaluation of Bone Marrow Stem Cells Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Regeneration of Maxillary Cystic Defects Versus Platelet Rich Fibrin with Bone Graft), which is not on this map. Cited by 194 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
194citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06662604 phase3not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Evaluation of Bone Marrow Stem Cells Concentrate with Platelet Rich Fibrin and Bone Graft in Bone Regeneration of Maxillary Cystic Defects Versus Platelet Rich Fibrin with Bone Graft (a Randomized Controlled Trial)

TypeinterventionalSponsorCairo UniversityRan2024 to 2026Enrolled22ConditionsMaxillary CystArmsBone marrow stem cells concentrate , platelet rich fibrin , bone graft, platelet rich fibrin and bone graft
3 · Its place in the literature

Who cites it

194 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  12. 14. Discogenic Low Back Pain.Pain practice : the official journal of World Institute of Pain · 2025
    Review
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134 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ross E B FitzsimmonsInstitute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, ON, Canada M5S 3G9.ORCID 0000-0002-4856-6252
Matthew S MazurekDivision of Gastroenterology and Hepatology, Department of Medicine, University of Calgary, Calgary, AB, Canada T2N 4Z6.ORCID 0000-0002-3361-7141
Agnes SoosInstitute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, ON, Canada M5S 3G9.ORCID 0000-0003-4185-1891
Craig A SimmonsInstitute of Biomaterials and Biomedical Engineering, University of Toronto, 164 College Street, Toronto, ON, Canada M5S 3G9.ORCID 0000-0001-7729-1772

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a result of over five decades of investigation, mesenchymal stromal/stem cells (MSCs) have emerged as a versatile and frequently utilized cell source in the fields of regenerative medicine and tissue engineering. In this review, we summarize the history of MSC research from the initial discovery of their multipotency to the more recent recognition of their perivascular identity

Identifiers

PMID30210552
PMCPMC6120267

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.