Evidence map›Paper›PMID 30237265›Full record

ArticleHaematologica2019

Machine learning reveals chronic graft-

Jocelyn S Gandelman, Michael T Byrne, Akshitkumar M Mistry, Hannah G Polikowsky, Kirsten E Diggins, Heidi Chen, Stephanie J Lee, Mukta Arora, Corey Cutler, Mary Flowers and 3 more

Abstract readMulticenter Study
In one paragraph

Article in Haematologica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jocelyn S GandelmanDepartment of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN.
Michael T ByrneDepartment of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN.
Akshitkumar M MistryVanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN.
Hannah G PolikowskyVanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN.
Kirsten E DigginsDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN.
Heidi ChenDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN.
Stephanie J LeeClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Mukta AroraDivision of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN.
Corey CutlerStem Cell/Bone Marrow Transplantation Program, Dana-Farber Cancer Institute, Boston, MA.
Mary FlowersClinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA.
Joseph PidalaH. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
Jonathan M IrishDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, TN jonathan.irish@vanderbilt.edu madan.jagasia@vanderbilt.edu.
Madan H JagasiaDepartment of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN jonathan.irish@vanderbilt.edu madan.jagasia@vanderbilt.edu.

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Douglas Yee · 1998 to 2026
$100.4M
Blood and Marrow Transplant Clinical Trials Network DCC- The Medical College of Wisconsin, Inc.U24HL138660 · NHLBI · MEDICAL COLLEGE OF WISCONSIN · PI Steven M. DeVine, Mehdi Hussain Hamadani · 2017 to 2026
$71.4M
Single-Cell Biology and Data Analysis Shared Resource (SCB-DA SR)U54CA217450 · NCI · VANDERBILT UNIVERSITY · PI WEAVER, ALISSA M · 2018 to 2022
$8.5M
Improving Outcomes Assessment in Chronic GVHDR01CA118953 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI LEE, STEPHANIE J · 2011 to 2025
$8.3M
Targeting the B Cell Receptor Signaling Network in LymphomaR00CA143231 · NCI · VANDERBILT UNIVERSITY · PI IRISH, JONATHAN MICHAEL · 2012 to 2014
$715k
NCI NIH HHS P30 CA077598NCI NIH HHS R00 CA143231NCI NIH HHS R01 CA118953NCI NIH HHS U24 CA076518NCI NIH HHS U54 CA217450NHLBI NIH HHS U24 HL138660
6 · The paper itself

Abstract

The application of machine learning in medicine has been productive in multiple fields, but has not previously been applied to analyze the complexity of organ involvement by chronic graft-

Indexed as

Graft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationMachine LearningAdultBiomarkersChronic DiseaseConsensusFemaleHumansMaleMiddle AgedNational Institutes of Health (U.S.)Observational Studies as TopicProspective StudiesSoftware ValidationBiomarkers

Identifiers

PMID30237265
PMCPMC6312024

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.