Evidence map›Paper›PMID 30251872›Full record

ArticleAIDS research and human retroviruses2018

Vitamin D Metabolites in Aging HIV-Infected Men: Does Inflammation Play a Role?

Long Zhang, Todd T Brown, Joseph B Margolick, Mallory D Witt, Frank J Palella, Lawrence A Kingsley, Andrew N Hoofnagle, Adrienne Tin, Lisa P Jacobson, Alison G Abraham

Abstract read
In one paragraph

Article in AIDS research and human retroviruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Long Zhang1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Todd T Brown2 Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine , Baltimore, Maryland.
Joseph B Margolick3 Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Mallory D Witt4 Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center , Torrance, California.
Frank J Palella5 Division of Infectious Diseases, Northwestern University Feinberg School of Medicine , Chicago, Illinois.
Lawrence A Kingsley6 Department of Infectious Diseases and Microbiology, University of Pittsburgh , Pittsburgh, Pennsylvania.
Andrew N Hoofnagle7 Departments of Laboratory Medicine and Medicine, University of Washington , Seattle, Washington.
Adrienne Tin1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Lisa P Jacobson1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Alison G Abraham1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health , Baltimore, Maryland.
Johns Hopkins University · USHarbor–UCLA Medical Center · USNorthwestern University · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

NATURAL HISTORY OF AIDS IN HOMOSEXUAL MENU01AI035040 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DETELS, ROGER, MARTINEZ-MAZA, OTONIEL · 1993 to 2018
$75.2M
University of Pittsburgh Multicenter AIDS Cohort Study (MACS)U01AI035041 · NIAID · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARTINSON, JEREMY JAMES, RINALDO, CHARLES R · 1993 to 2018
$71.4M
Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Anna Palmer Durbin · 2012 to 2026
$67.0M
MULTICENTER AIDS COHORT STUDYU01AI035039 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI WOLINSKY, STEVEN M · 1993 to 2018
$66.4M
Multicenter Aids Cohort Study- Part B (Baltimore Site)U01AI035042 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T, MARGOLICK, JOSEPH B. · 1993 to 2018
$61.5M
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1M
Center for the Analysis & Management of the Multicenter AIDS Cohort StudyUM1AI035043 · NIAID · JOHNS HOPKINS UNIVERSITY · PI D'SOUZA, GYPSYAMBER, JACOBSON, LISA P · 2012 to 2018
$20.7M
Mentoring in Endocrine and Metabolic Abnormalities in HIV and AgingK24AI120834 · NIAID · JOHNS HOPKINS UNIVERSITY · PI BROWN, TODD T · 2015 to 2025
$1.8M
Vitamin D Deficiency, Inflammation and Age-related disease in HIV-Infected MenR21AI109817 · NIAID · JOHNS HOPKINS UNIVERSITY · PI ABRAHAM, ALISON G · 2014 to 2015
$327k
NCATS NIH HHS UL1 TR001079NIAID NIH HHS K24 AI120834NIAID NIH HHS P30 AI094189NIAID NIH HHS R21 AI109817NIAID NIH HHS U01 AI035039NIAID NIH HHS U01 AI035040NIAID NIH HHS U01 AI035041NIAID NIH HHS U01 AI035042NIAID NIH HHS UM1 AI035043
6 · The paper itself

Abstract

The inflammatory context of HIV infection has been posited to contribute to the higher comorbidity risk noted in HIV-infected populations. One possible pathway may involve 1,25-dihydroxyvitamin D [1,25(OH)

Indexed as

biomarkerHIV infectedinflammationvitamin D

Identifiers

PMID30251872
PMCPMC6306657
OpenAlexW2893117444

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.