Evidence map›Paper›PMID 30274201›Full record

ArticleInternational journal of molecular sciences2018

Antimicrobial Coatings from Hybrid Nanoparticles of Biocompatible and Antimicrobial Polymers.

Carolina Nascimento Galvão, Luccas Missfeldt Sanches, Beatriz Ideriha Mathiazzi, Rodrigo Tadeu Ribeiro, Denise Freitas Siqueira Petri, Ana Maria Carmona-Ribeiro

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Emerging Cationic Nanovaccines.Pharmaceutics · 2024
    Review
  5. Article
  6. Article
  7. Supramolecular Nanostructures for Vaccines.Biomimetics (Basel, Switzerland) · 2021
    Review
  8. Article
  9. Antimicrobial Polymer-Based Assemblies: A Review.International journal of molecular sciences · 2021
    Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Cationic Nanostructures for Vaccines Design.Biomimetics (Basel, Switzerland) · 2020
    Review
  15. Article
  16. Article
  17. Article
  18. Polymeric Systems as Antimicrobial or Antifouling Agents.International journal of molecular sciences · 2019
    Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carolina Nascimento GalvãoBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. carolinagalvao@usp.br.
Luccas Missfeldt SanchesBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. luccas.sanches@hotmail.com.
Beatriz Ideriha MathiazziBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. bemathi@usp.br.
Rodrigo Tadeu RibeiroBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. rodrigo@iq.usp.br.ORCID 0000-0002-5099-4256
Denise Freitas Siqueira PetriDepartamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. dfsp@usp.br.ORCID 0000-0003-4814-8357
Ana Maria Carmona-RibeiroBiocolloids Laboratory, Departamento de Bioquímica, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes 748, 05508-000 São Paulo, Brazil. amcr@usp.br.ORCID 0000-0001-8500-2707

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 302352/2014-7
6 · The paper itself

Abstract

Hybrid nanoparticles of poly(methylmethacrylate) synthesized in the presence of poly (diallyldimethyl ammonium) chloride by emulsion polymerization exhibited good colloidal stability, physical properties, and antimicrobial activity but their synthesis yielded poor conversion. Here we create antimicrobial coatings from casting and drying of the nanoparticles dispersions onto model surfaces such as those of silicon wafers, glass coverslips, or polystyrene sheets and optimize conversion using additional stabilizers such as cetyltrimethyl ammonium bromide, dioctadecyldimethyl ammonium bromide, or soybean lecithin during nanoparticles synthesis. Methodology included dynamic light scattering, determination of wettability, ellipsometry of spin-coated films, scanning electron microscopy, and determination of colony forming unities (log CFU/mL) of bacteria after 1 h interaction with the coatings. The additional lipids and surfactants indeed improved nanoparticle synthesis, substantially increasing the conversion rates by stabilizing the monomer droplets in dispersion during the polymerization. The coatings obtained by spin-coating or casting of the nanoparticles dispersions onto silicon wafers were hydrophilic with contact angles increasing with the amount of the cationic polymer in the nanoparticles. Against

Indexed as

Anti-Bacterial AgentsCoated Materials, BiocompatibleColloidsEscherichia coliMicrobial Sensitivity TestsNanoparticlesPolyethylenesPolymersPolymethyl MethacrylateQuaternary Ammonium CompoundsSolventsStaphylococcus aureusSurface-Active AgentsAnti-Bacterial AgentsCoated Materials, BiocompatibleColloidsPolyethylenesPolymersPolymethyl Methacrylatepoly-N,N-dimethyl-N,N-diallylammonium chlorideQuaternary Ammonium CompoundsSolventsSurface-Active Agentsantimicrobial polymerbacteria viabilitybactericidal coatingsbiocompatible polymercoatings from nanoparticlescoatings wettabilitydynamic light scatteringEscherichia colimicrobicidal coatingsStaphylococcus aureus

Identifiers

PMID30274201
PMCPMC6213362

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.