ArticleInternational journal of molecular sciences2018
Correlation between Diabetes Mellitus and Knee Osteoarthritis: A Dry-To-Wet Lab Approach.
Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 45 citations in OpenAlex.
- Psychosocial and physiological health outcomes of outdoor green exercise versus indoor exercise in knee osteoarthritis patients coexisting with type 2 diabetes mellitus: a randomized controlled trial.Frontiers in endocrinology · 2025Trial
- Different intensities of aerobic training for patients with type 2 diabetes mellitus and knee osteoarthritis: a randomized controlled trial.Frontiers in endocrinology · 2024Trial
- Mapping the intersection of social status and comorbidity in knee osteoarthritis: A WOMAC-based study.PloS one · 2026Article
- Causal inference study on the effect of exogenous insulin on the risk of osteoarthritis.Medicine · 2025Article
- Inflammatory mechanisms underlying metabolic syndrome-associated and potential treatments.Osteoarthritis and cartilage open · 2025Article
- Exploring Mesenchymal Stromal Cells as a Potential Therapy for Comorbid Osteoarthritis and Type 2 Diabetes Mellitus.Stem cells international · 2025Review
- Emerging therapeutic potential of glucagon-like Peptide-1 receptor agonists in knee osteoarthritis: a systematic review.Frontiers in pharmacology · 2025Review
- Identification and validation of up-regulated TNFAIP6 in osteoarthritis with type 2 diabetes mellitus.Scientific reports · 2024Article
- Diabetes and Functional Impairment in Osteoarthritis: Investigating Correlations, Associations, and Progression.Cureus · 2024Article
- Metabolic syndrome increases osteoarthritis risk: findings from the UK Biobank prospective cohort study.BMC public health · 2024Article
- Evidence supported by Mendelian randomization: impact on inflammatory factors in knee osteoarthritis.Frontiers in medicine · 2024Article
- Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysis.PloS one · 2024Article
- Causal Effect of Higher Glycated Hemoglobin (HbA1c) Levels on Knee Osteoarthritis Risk: A Mendelian Randomization Study.Rheumatology and therapy · 2023Article
- Potential Protective Role of Galectin-3 in Patients with Gonarthrosis and Diabetes Mellitus: A Cross-Sectional Study.International journal of environmental research and public health · 2022Article
- Review
- Proline-Serine-Threonine Phosphatase-Interacting Protein 2 Alleviates Diabetes Mellitus-Osteoarthritis in Rats through Attenuating Synovial Inflammation and Cartilage Injury.Orthopaedic surgery · 2021Article
- Gait Speed as a Predictor for Diabetes Incidence in People with or at Risk of Knee Osteoarthritis: A Longitudinal Analysis from the Osteoarthritis Initiative.International journal of environmental research and public health · 2021Article
- Systemic and ocular diseases associated with the development of diabetic macular edema among Japanese patients with diabetes mellitus.BMC ophthalmology · 2020Article
- Insulin Resistance in Osteoarthritis: Similar Mechanisms to Type 2 Diabetes Mellitus.Journal of nutrition and metabolism · 2020Review
- Osteoarthritis and Cartilage Regeneration: Focus on Pathophysiology and Molecular Mechanisms.International journal of molecular sciences · 2019Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 3 countries.
Funding
Abstract
Recent years have witnessed an increased prevalence of knee osteoarthritis (KOA) among diabetes mellitus (DM) patients-conditions which might share common risk factors such as obesity and advanced aging. Therefore, we conducted dry-to-wet lab research approaches to assess the correlation of type 1 DM (T1DM) and type 2 DM (T2DM) with KOA among all age and genders of Taiwanese population. The strength of association (odds ratio: OR) was analyzed using a phenome-wide association study portal. Populations of 37,353 T1DM and 1,218,254 T2DM were included. We observed a significant association of KOA with T1DM (OR: 1.40 (1.33⁻1.47),
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.