Trial reportJournal of general internal medicine2018
Quality Improvement and Personalization for Statins: the QUIPS Quality Improvement Randomized Trial of Veterans' Primary Care Statin Use.
Trial report in Journal of general internal medicine, 2018. The graph read 2 numbers from its abstract, feeding 1 cell of the map: it . An erratum has been issued. It reports registered trial NCT02820870. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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KEY RESULTS: Among 3787 visits to 43 primary care providers, being in the intervention arm tripled the odds of patients being prescribed an appropriate statin (OR 3.0, 95% CI 1.8-4.9), though the effect resolved after the personalized decision support ended (OR 1.7, 95% CI 0.99-2.77).
KEY RESULTS: Among 3787 visits to 43 primary care providers, being in the intervention arm tripled the odds of patients being prescribed an appropriate statin (OR 3.0, 95% CI 1.8-4.9), though the effect resolved after the personalized decision support ended (OR 1.7, 95% CI 0.99-2.77).
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Where it lands on the map
Rows are treatments, columns are outcomes. The coloured squares are the cells this paper feeds, coloured by the vote it casts there. Click one to jump to what this paper adds to it.
What it adds to each cell
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Statins×costs & health-care use
No readable resultOpen on the map →What to test next →1 readable study in this cell: 0 favour the treatment, 0 find no difference, 1 favour the comparator.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Quality Improvement and Personalization for Statins (QUIPS) (QUE 15-286)
Open the trial in the graphWho cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026Pooled it
- Effect of Pharmacist Email Alerts on Concurrent Prescribing of Opioids and Benzodiazepines by Prescribers and Primary Care Managers: A Randomized Clinical Trial.JAMA health forum · 2022Trial
- Article
- Influencing Appropriate Statin Use in a Charity Care Primary Clinic.Healthcare (Basel, Switzerland) · 2022Article
- Factors affecting statin uptake among people living with HIV: primary care provider perspectives.BMC family practice · 2021Article
- Understanding providers' attitudes and key concerns toward incorporating CVD risk prediction into clinical practice: a qualitative study.BMC health services research · 2021Article
- Barriers to Implementing Cardiovascular Risk Calculation in Primary Care: Alignment With the Consolidated Framework for Implementation Research.American journal of preventive medicine · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
Abstract
The marked sentences are the ones the graph read a number from.
backgroundImplementation of new practice guidelines for statin use was very poor.
objectiveTo test a multi-component quality improvement intervention to encourage use of new guidelines for statin use.
designCluster-randomized, usual-care controlled trial.
participantsThe study population was primary care visits for patients who were recommended statins by the 2013 guidelines, but were not receiving them. We excluded patients who were over 75 years old, or had an ICD9 or ICD10 code for end-stage renal disease, muscle pain, pregnancy, or in vitro fertilization in the 2 years prior to the study visit.
interventionsA novel quality improvement intervention consisting of a personalized decision support tool, an educational program, a performance measure, and an audit and feedback system. Randomization was at the level of the primary care team. MAIN MEASURES: Our primary outcome was prescription of a medium- or high-strength statin. We studied how receiving the intervention changed care during the quality improvement intervention compared to before it and if that change continued after the intervention. KEY
resultsAmong 3787 visits to 43 primary care providers, being in the intervention arm tripled the odds of patients being prescribed an appropriate statin (OR 3.0, 95% CI 1.8-4.9), though the effect resolved after the personalized decision support ended (OR 1.7, 95% CI 0.99-2.77).
conclusionsA simple, personalized quality improvement intervention is promising for enabling the adoption of new guidelines. CLINICALTRIALS. GOV IDENTIFIER: NCT02820870.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.