Evidence map›Paper›PMID 30295797›Full record

ArticleEuropean heart journal2018

Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology.

Christoph Maack, Michael Lehrke, Johannes Backs, Frank R Heinzel, Jean-Sebastien Hulot, Nikolaus Marx, Walter J Paulus, Patrick Rossignol, Heinrich Taegtmeyer, Johann Bauersachs and 25 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European heart journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 112 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
112citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

112 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Mechano-energetic uncoupling in heart failure.Nature reviews. Cardiology · 2025
    Review
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  16. Article
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  18. Novel Cardiometabolic Medications in the Cardiovascular-Kidney-Metabolic Syndrome Era.The Journal of clinical endocrinology and metabolism · 2025 · on this map
    Review
  19. Article
  20. Article

52 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Christoph MaackComprehensive Heart Failure Center, University Clinic Würzburg, Würzburg, Germany.
Michael LehrkeDepartment of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Johannes BacksDepartment of Molecular Cardiology and Epigenetics, University of Heidelberg, Heidelberg, Germany.
Frank R HeinzelDepartment of Cardiology, Charité-Universitätsmedizin, Berlin, Germany.
Jean-Sebastien HulotParis Cardiovascular Research Center PARCC, INSERM UMR970, CIC 1418, and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Paris, France.
Nikolaus MarxDepartment of Internal Medicine I, University Hospital Aachen, Aachen, Germany.
Walter J PaulusDepartment of Physiology, VU University Medical Center, Amsterdam, The Netherlands.
Patrick RossignolInserm, Centre d'Investigations Cliniques-Plurithématique 14-33, Inserm U1116, CHRU Nancy, Université de Lorraine, and F-CRIN INI-CRCT (Cardiovascular and Renal Clinical Trialists), Nancy, France.
Heinrich TaegtmeyerDepartment of Internal Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, USA.
Johann BauersachsDepartment of Cardiology and Angiology, Hannover Medical School, Hannover, Germany.
Antoni Bayes-GenisHeart Failure Unit and Cardiology Service, Hospital Universitari Germans Trias i Pujol, CIBERCV, Badalona, Spain.
Dirk BrutsaertProf-Emer, University of Antwerp, Antwerp, Belgium.
Heiko BuggerCardiology and Angiology, Heart Center, University of Freiburg, Freiburg, Germany.
Kieran ClarkeDepartment of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK.
Francesco CosentinoDepartment of Medicine Solna, Cardiology Unit, Karolinska Institute and Karolinska University Hospital, Stockholm, Sweden.
Gilles De KeulenaerLaboratory of Physiopharmacology, University of Antwerp, Antwerp, Belgium.
Alessandra Dei CasDepartment of Medicine and Surgery, Endocrinology and Metabolism, University of Parma, Parma, Italy.
Arantxa GonzálezProgram of Cardiovascular Diseases, Centre for Applied Medical Research, University of Navarra, Pamplona and CIBERCV, Carlos III Institute of Health, Madrid, Spain.
Martin HuelsmannDivision of Cardiology, Department of Medicine II, Medical University of Vienna, Vienna, Austria.
Guido IaccarinoDepartment of Medicine, Surgery and Dentistry, University of Salerno, Baronissi, Italy.
Ida Gjervold LundeInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Alexander R LyonCardiovascular Research Centre, Royal Brompton Hospital; National Heart and Lung Institute, Imperial College London, London, UK.
Piero PolleselloFaculty of Medicine, University of Helsinki, Helsinki, Finland.
Graham RenaDivision of Molecular and Clinical Medicine, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK.
Niels P RiksenDepartment of Internal Medicine, Radboud University Medical Center, Nijmegen, the Netherlands.
Giuseppe RosanoCardiovascular Clinical Academic Group, St George's Hospitals NHS Trust University of London, London, UK.
Bart StaelsUniversity of Lille-EGID, Lille, France.
Linda W van LaakeDepartment of Cardiology, Heart and Lungs Division, and Regenerative Medicine Centre, University Medical Centre Utrecht, Utrecht, the Netherlands.
Christoph WannerWürzburg University Clinic, Würzburg, Germany.
Dimitrios FarmakisHeart Failure Unit, Athens University Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece.
Gerasimos FilippatosHeart Failure Unit, Athens University Hospital Attikon, National and Kapodistrian University of Athens, Athens, Greece.
Frank RuschitzkaUniversity Heart Centre, University Hospital Zurich, Zurich, Switzerland.
Petar SeferovicDepartment of Cardiology, Belgrade University Medical Centre, Belgrade, Serbia.
Rudolf A de BoerDepartment of Cardiology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Stephane HeymansDepartment of Cardiology, Cardiovascular Research Institute Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.

Funding

Glucolipotoxicity and Cardiac Dysfunction in ObesityR01HL073162 · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 2003 to 2005
$1.5M
SWITCHING OF METABOLIC GENES IN UNLOADED HEARTR01HL061483 · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · 1999 to 2004
$1.3M
Medical Research Council MR/K012924/1NHLBI NIH HHS R01 HL061483NHLBI NIH HHS R01 HL073162
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AgedAged, 80 and overComorbidityDiabetes MellitusEuropeFemaleHeart FailureHumansHypoglycemic AgentsInsulin ResistanceMaleObesityRenal Insufficiency, ChronicSocieties, MedicalSocioeconomic FactorsSulfonylurea CompoundsHypoglycemic AgentsSulfonylurea Compounds

Identifiers

PMID30295797
PMCPMC6302261

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.