Evidence map›Paper›PMID 30314980›Full record

ArticleRNA (New York, N.Y.)2019

Hnrnpab regulates neural cell motility through transcription of Eps8.

Alexa A Lampasona, Kevin Czaplinski

Open access · bronzeAbstract read
In one paragraph

Article in RNA (New York, N.Y.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Alexa A LampasonaProgram in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, New York 11749, USA.
Kevin CzaplinskiCenters for Molecular Medicine, Stony Brook University, Stony Brook, New York 11749, USA.ORCID 0000-0002-7520-8215
Stony Brook Medicine · USStony Brook University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell migration requires a complicated network of structural and regulatory proteins. Changes in cellular motility can impact migration as a result of cell-type or developmental stage regulated expression of critical motility genes. Hnrnpab is a conserved RNA-binding protein found as two isoforms produced by alternative splicing. Its expression is enriched in the subventricular zone (SVZ) and the rostral migratory stream within the brain, suggesting possible support of the migration of neural progenitor cells in this region. Here we show that the migration of cells from the SVZ of developing

Indexed as

Adaptor Proteins, Signal TransducingAlternative SplicingAnimalsCell LineCell MovementGene Expression Regulation, DevelopmentalHeterogeneous-Nuclear Ribonucleoprotein Group A-BHumansLateral VentriclesMiceMice, Inbred C57BLMice, KnockoutModels, NeurologicalNeuronsProtein IsoformsRNA Recognition MotifAdaptor Proteins, Signal TransducingEps8 protein, mouseHeterogeneous-Nuclear Ribonucleoprotein Group A-BProtein Isoformscell motilityregulation of gene expressionRNA binding protein

Identifiers

PMID30314980
PMCPMC6298563
OpenAlexW2896253235

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.