ReviewCold Spring Harbor perspectives in medicine2019
Toward the Optical Cochlear Implant.
Review in Cold Spring Harbor perspectives in medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- From optical control to translational readiness: an evidence-tiered framework for optogenetics in neuromuscular and neurological disorders.Materials today. Bio · 2026Review
- From Brain Lobes to Neurons: Navigating the Brain Using Advanced 3D Modeling and Visualization Tools.Journal of imaging · 2025Article
- Review
- A Spectrum of Intraoperative and Postoperative Complications of Cochlear Implants: A Critical Review.Cureus · 2022Review
- Conversations in Cochlear Implantation: The Inner Ear Therapy of Today.Biomolecules · 2022Review
- Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Molecular Biology of Microbial Rhodopsins.Methods in molecular biology (Clifton, N.J.) · 2022Review
- Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants.Computational and structural biotechnology journal · 2022Article
- Channel Interaction During Infrared Light Stimulation in the Cochlea.Lasers in surgery and medicine · 2021Article
- Utility of red-light ultrafast optogenetic stimulation of the auditory pathway.EMBO molecular medicine · 2021Article
- Current Topics of Optogenetics for Medical Applications Toward Therapy.Advances in experimental medicine and biology · 2021Article
- Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants.Frontiers in molecular neuroscience · 2021Article
- Shedding light on optical cochlear implant progress.EMBO molecular medicine · 2020Article
- Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents.Science translational medicine · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
When hearing fails, cochlear implants (CIs) provide open speech perception to most of the currently half a million CI users. CIs bypass the defective sensory organ and stimulate the auditory nerve electrically. The major bottleneck of current CIs is the poor coding of spectral information, which results from wide current spread from each electrode contact. As light can be more conveniently confined, optical stimulation of the auditory nerve presents a promising perspective for a fundamental advance of CIs. Moreover, given the improved frequency resolution of optical excitation and its versatility for arbitrary stimulation patterns the approach also bears potential for auditory research. Here, we review the current state of the art focusing on the emerging concept of optogenetic stimulation of the auditory pathway. Developing optogenetic stimulation for auditory research and future CIs requires efforts toward viral gene transfer to the neurons, design and characterization of appropriate optogenetic actuators, as well as engineering of multichannel optical implants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.