Evidence map›Paper›PMID 30323600›Full record

ArticleNeuropsychiatric disease and treatment2018

Association between reduced quality of life and depression in patients with type 2 diabetes mellitus: a cohort study in a Mexican population.

Isela Esther Juárez-Rojop, Carlos Mario Fortuny-Falconi, Thelma Beatriz González-Castro, Carlos Alfonso Tovilla-Zárate, Mario Villar-Soto, Ester Rodríguez Sanchez, Yazmín Hernández-Díaz, María Lilia López-Narvaez, Jorge L Ble-Castillo, Nonanzit Pérez-Hernández and 1 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04131582 (Effect of a Quadruple Therapy on Pancreatic Islet Function, Insulin Resistance and Cardiovascular Function in Patients With Mixed Prediabetes and Obesity), which is not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04131582 phase3unknown statusstarted 2019, after this paper: background citation

Effect of a Quadruple Therapy on Pancreatic Islet Function, Insulin Resistance and Cardiovascular Function in Patients With Mixed Prediabetes and Obesity: Randomized Clinical Trial

Ran2019Enrolled34Registered outcomes4Posted comparisons0ConditionsInsulin Resistance, Prediabetic StateArmsLinagliptin + metformin and Empagliflozin + metformin, Metformin
Open the trial in the graph
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. The social determinants of health-related quality of life among people with chronic disease: a systematic literature review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Decreased Quality of Life in Individuals with Type 2 Diabetes Mellitus Is Associated with Emotional Distress.International journal of environmental research and public health · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Isela Esther Juárez-RojopMultidisciplinary Academic Division of Health Sciences, Juarez Autonomous University of Tabasco, Villahermosa, Tabasco, Mexico.
Carlos Mario Fortuny-FalconiMultidisciplinary Academic Division of Comalcalco, Juarez Autonomous University of Tabasco, Comalcalco, Tabasco, Mexico, alfonso_tovillaz@yahoo.com.mx.
Thelma Beatriz González-CastroMultidisciplinary Academic Division of Jalpa de Méndez, Juarez Autonomous University of Tabasco, Jalpa de Méndez, Tabasco, Mexico.
Carlos Alfonso Tovilla-ZárateMultidisciplinary Academic Division of Comalcalco, Juarez Autonomous University of Tabasco, Comalcalco, Tabasco, Mexico, alfonso_tovillaz@yahoo.com.mx.
Mario Villar-SotoPsychiatric Care Services, Hospital of high specialty "Gustavo A. Rovirosa Pérez", Ministry of Health, Villahermosa, Tabasco, Mexico.
Ester Rodríguez SanchezPsychiatric Care Services, Hospital of high specialty "Gustavo A. Rovirosa Pérez", Ministry of Health, Villahermosa, Tabasco, Mexico.
Yazmín Hernández-DíazMultidisciplinary Academic Division of Jalpa de Méndez, Juarez Autonomous University of Tabasco, Jalpa de Méndez, Tabasco, Mexico.
María Lilia López-NarvaezPediatric Care Services, General Hospital of Yajalon "Dr. Manuel Velasco Suarez", Yajalon, Chiapas, Mexico.
Jorge L Ble-CastilloMultidisciplinary Academic Division of Health Sciences, Juarez Autonomous University of Tabasco, Villahermosa, Tabasco, Mexico.
Nonanzit Pérez-HernándezDepartment of Molecular Biology, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.
José Manuel Rodríguez-PérezDepartment of Molecular Biology, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.
Universidad Juárez Autónoma de Tabasco · MXInstituto Nacional de Cardiología · MXHospital General Dr. Manuel Gea Gonzalez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetes mellitus is a chronic disease that requires attention and commitment on the part of patients; improving the quality of life of these patients reduces health costs, morbidity, and mortality. We focused on investigating the factors related with the quality of life and depression symptomatology in patients with type 2 diabetes. PARTICIPANTS AND

methodsA total of 173 Mexican patients with type 2 diabetes were recruited. An interview face-to-face, a sociodemographic characteristics questionnaire, the Short Form 36 (SF-36), and the Clinical Epidemiological Studies of Depression were applied. The biochemical parameters measured were blood glucose, cholesterol, triacylglycerol levels, and glycated hemoglobin.

resultsIn all SF-36 subscales, female patients had lower scores in comparison with male patients; individuals ≥65 years of age showed less physical function. We observed that married patients presented a better quality of life than people who were widowed or divorced (

conclusionOur results suggest that untreated and unrecognized depression can decrease the quality of life in patients with diabetes mellitus type 2. Therefore, health care professionals need to consider these findings when treating patients with diabetes. Due to the limited number of patients included in the present study, more studies are needed, studying larger samples in order to provide conclusive results.

Indexed as

depressiondiabetesMexican populationquality of life

Identifiers

PMID30323600
PMCPMC6175568
OpenAlexW2895154760

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.