Evidence map›Paper›PMID 30327445›Full record

ArticlemBio2018

A Bacteriophage T4 Nanoparticle-Based Dual Vaccine against Anthrax and Plague.

Pan Tao, Marthandan Mahalingam, Jingen Zhu, Mahtab Moayeri, Jian Sha, William S Lawrence, Stephen H Leppla, Ashok K Chopra, Venigalla B Rao

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 92 citations in OpenAlex.

  1. Review
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  4. Human anthrax vaccines: Current status and future prospects.Human vaccines & immunotherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Pan TaoDepartment of Biology, The Catholic University of America, Washington, DC, USA.
Marthandan MahalingamDepartment of Biology, The Catholic University of America, Washington, DC, USA.
Jingen ZhuDepartment of Biology, The Catholic University of America, Washington, DC, USA.
Mahtab MoayeriMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Jian ShaDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
William S LawrenceDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA.
Stephen H LepplaMicrobial Pathogenesis Section, Laboratory of Parasitic Diseases, NIAID, NIH, Bethesda, Maryland, USA.
Ashok K ChopraDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, Texas, USA achopra@utmb.edu rao@cua.edu.
Venigalla B RaoDepartment of Biology, The Catholic University of America, Washington, DC, USA achopra@utmb.edu rao@cua.edu.
The University of Texas Medical Branch at Galveston · USCatholic University of America · USNational Institute of Allergy and Infectious Diseases · USUniversity of America · US

Funding

Vaccines and Therapeutics for AnthraxZIAAI000929 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI LEPPLA, STEPHEN · 2009 to 2025
$15.9M
Identification of New Antigens for a Plague VaccineR01AI064389 · NIAID · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI CHOPRA, ASHOK K · 2005 to 2015
$3.8M
Single Dose, Multivalent, Anthrax Plague Vaccines using Bacteriophage T4 NanopartR01AI111538 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2014 to 2018
$3.6M
A Multicomponent Anthrax Vaccine using Phage T4 DisplayU01AI056443 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2003 to 2007
$3.3M
Multivalent Plague, Anthrax Vaccines Using Bacteriophage T4 DisplayU01AI082086 · NIAID · CATHOLIC UNIVERSITY OF AMERICA · PI RAO, VENIGALLA B. · 2009 to 2013
$2.2M
NIAID NIH HHS R01 AI064389NIAID NIH HHS R01 AI111538NIAID NIH HHS U01 AI056443NIAID NIH HHS U01 AI082086
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacteriophage T4AnimalsAnthraxAnthrax VaccinesAntibodies, BacterialAntigens, BacterialBacillus anthracisBacterial ProteinsBacterial ToxinsCapsid ProteinsFemaleMaleMiceMice, Inbred BALB CNanoparticlesPlagueanthrax toxinAnthrax VaccinesAntibodies, BacterialAntigens, BacterialBacterial ProteinsBacterial Toxinscaf1 protein, Yersinia pestisCapsid ProteinsLcrV protein, YersiniaPlague VaccinePore Forming Cytotoxic Proteinssmall outer capsid protein, bacteriophage T4anthrax vaccinebacteriophage T4biodefenseplague vaccinesmall outer capsid proteinvaccine deliveryvirus nanoparticles

Identifiers

PMID30327445
PMCPMC6191538
OpenAlexW2895888270

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.