Evidence map›Paper›PMID 30327872›Full record

ArticleActa diabetologica2018

Measurement of corneal thickness, optic nerve sheath diameter and retinal nerve fiber layer as potential new non-invasive methods in assessing a risk of cerebral edema in type 1 diabetes in children.

Krzysztof Jeziorny, Anna Niwald, Agnieszka Moll, Katarzyna Piasecka, Aleksandra Pyziak-Skupien, Arleta Waszczykowska, Dobromiła Baranska, Beata Malachowska, Agnieszka Szadkowska, Wojciech Mlynarski and 1 more

Open access · hybridAbstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta diabetologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Optic Nerve Ultrasound Evaluation in Children: A Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Krzysztof JeziornyDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Sporna Str. 36/50, 91-738, Lodz, Poland.
Anna NiwaldOutpatient Clinic of Pediatric Ophthalmology, Central Clinical Hospital, Lodz, Poland.
Agnieszka MollOutpatient Clinic of Pediatric Ophthalmology, Central Clinical Hospital, Lodz, Poland.
Katarzyna PiaseckaOutpatient Clinic of Pediatric Ophthalmology, Central Clinical Hospital, Lodz, Poland.
Aleksandra Pyziak-SkupienDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Sporna Str. 36/50, 91-738, Lodz, Poland.
Arleta WaszczykowskaDepartment of Ophthalmology and Vision Rehabilitation, Medical University of Lodz, Lodz, Poland.
Dobromiła BaranskaDepartment of Diagnostic Imaging, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.
Beata MalachowskaDepartment of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland.
Agnieszka SzadkowskaDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Sporna Str. 36/50, 91-738, Lodz, Poland.
Wojciech MlynarskiDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Sporna Str. 36/50, 91-738, Lodz, Poland.
Agnieszka ZmyslowskaDepartment of Pediatrics, Oncology, Hematology and Diabetology, Medical University of Lodz, Sporna Str. 36/50, 91-738, Lodz, Poland. agnieszka.zmyslowska@umed.lodz.pl.ORCID http://orcid.org/0000-0001-8781-4469
Medical University of Lodz · PLCentral Clinical Hospital · PLPolish Mother’s Memorial Hospital Research Institute · PL

Funding

Narodowe Centrum Nauki No 2014/15/B/NZ5/01579
6 · The paper itself

Abstract

aimsSome patients with diabetic ketoacidosis develop cerebral edema (CE) in the course of type 1 diabetes mellitus (T1D), which may result in central nervous system disorders and high mortality. The imperfection of existing neuroimaging techniques for early recognition of CE forces us to search for the new and non-invasive methods. The aim of the study was to assess the usefulness of new methods (pachymetry, transorbital ultrasonography-USG, optical coherence tomography-OCT study) in the assessment of the risk of CE occurrence in children with newly diagnosed T1D.

methodsThe study group included 50 children with newly diagnosed T1D, 54 patients with long-term T1D as a reference group and 40 children without glucose tolerance disorders as controls. In all subjects, a corneal thickness (CCT) index with pachymeter, optic nerve sheath diameter (ONSD) using transorbital USG and retinal nerve fiber layer (RNFL) during OCT study were measured and compared with selected clinical parameters of T1D.

resultsIn patients from a study group at onset of T1D, the higher CCT (p < 0.001) and ONSD (p < 0.001) values were observed as compared to the results obtained after 48 h of metabolic compensation. The ONSD correlated negatively with pH value (r = - 0.64; p < 0.001), BE (r = - 0.54, p < 0.001) and HCO

conclusionsTransorbital USG and pachymetry may serve as the potential promising methods for the non-invasive assessment of the increased risk of development of CE in patients with T1D.

Indexed as

Corneal PachymetryAdolescentBrain EdemaCase-Control StudiesChildDiabetes Mellitus, Type 1Diabetic KetoacidosisDiabetic RetinopathyFemaleHumansMaleNerve FibersOptic NervePredictive Value of TestsRetinaRetinal Ganglion CellsCCTCerebral edemaONSDRNFLType 1 diabetes

Identifiers

PMID30327872
PMCPMC6244862
OpenAlexW2895873477

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.