Evidence map›Paper›PMID 30333188›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Transcription initiation defines kinetoplast RNA boundaries.

François M Sement, Takuma Suematsu, Liye Zhang, Tian Yu, Lan Huang, Inna Aphasizheva, Ruslan Aphasizhev

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 23 citations in OpenAlex.

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  14. Mitochondrial RNA quality control in trypanosomes.Wiley interdisciplinary reviews. RNA · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

François M SementDepartment of Molecular and Cell Biology, Boston University, Boston, MA 02118.
Takuma SuematsuDepartment of Molecular and Cell Biology, Boston University, Boston, MA 02118.
Liye ZhangSchool of Life Science and Technology, ShanghaiTech University, Shanghai 200031, China.
Tian YuDepartment of Molecular and Cell Biology, Boston University, Boston, MA 02118.
Lan HuangDepartment of Physiology and Biophysics, School of Medicine, University of California, Irvine, CA 92697.
Inna AphasizhevaDepartment of Molecular and Cell Biology, Boston University, Boston, MA 02118.
Ruslan AphasizhevDepartment of Molecular and Cell Biology, Boston University, Boston, MA 02118; ruslana@bu.edu.ORCID 0000-0002-4595-6618
Boston University · USShanghaiTech University · CNUniversity of California, Irvine · US

Funding

Proteomics of the Proteasome Interacting NetworksR01GM074830 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUANG, LAN · 2005 to 2022
$6.1M
Guide RNA Binding ComplexR01AI101057 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Ruslan Afasizhev · 2012 to 2026
$6.0M
REPEAT-CONTAINING RNA BINDING PROTEINS OF TRYPANOSOMESR01AI113157 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI AFASIZHEVA, INNA · 2015 to 2024
$4.6M
Structures and Functions of RNA Editing TUTasesR01AI091914 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI AFASIZHEV, RUSLAN · 2011 to 2020
$4.4M
In Vivo Interactome and Dynamics of Cullin-Ring LigasesR01GM106003 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUANG, LAN, RYCHNOVSKY, SCOTT D. · 2013 to 2016
$772k
NIAID NIH HHS R01 AI091914NIAID NIH HHS R01 AI101057NIAID NIH HHS R01 AI113157NIGMS NIH HHS R01 GM074830NIGMS NIH HHS R01 GM106003
6 · The paper itself

Abstract

Mitochondrial genomes are often transcribed into polycistronic RNAs punctuated by tRNAs whose excision defines mature RNA boundaries. Although kinetoplast DNA lacks tRNA genes, it is commonly held that in

Indexed as

DNA, KinetoplastMitochondriaPolyadenylationProtozoan ProteinsRNA, AntisenseRNA EditingRNA, ProtozoanTranscription, GeneticTrypanosoma brucei bruceiDNA, KinetoplastProtozoan ProteinsRNA, AntisenseRNA, ProtozoanmitochondriaNUDIX hydrolaseRNA stabilitytranscriptionTrypanosoma

Identifiers

PMID30333188
PMCPMC6217428
OpenAlexW2808507169

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.