Evidence map›Paper›PMID 30340320›Full record

ReviewMolecules (Basel, Switzerland)2018

Use of Nutraceuticals in Angiogenesis-Dependent Disorders.

Lucia Morbidelli, Erika Terzuoli, Sandra Donnini

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  4. Article
  5. Review
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  7. Review
  8. Liraglutide Increases VEGF ExpressionFrontiers in pharmacology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lucia MorbidelliDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy. lucia.morbidelli@unisi.it.ORCID 0000-0001-8148-7049
Erika TerzuoliDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy. terzuoli8@unisi.it.ORCID 0000-0001-9248-4505
Sandra DonniniDepartment of Life Sciences, University of Siena, Via A. Moro 2, 53100 Siena, Italy. sandra.donnini@unisi.it.ORCID 0000-0001-6617-1644
University of Siena · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The term of angiogenesis refers to the growth of new vessels from pre-existing capillaries. The phenomenon is necessary for physiological growth, repair and functioning of our organs. When occurring in a not regulated manner, it concurs to pathological conditions as tumors, eye diseases, chronic degenerative disorders. On the contrary insufficient neovascularization or endothelial disfunction accompanies ischemic and metabolic disorders. In both the cases an inflammatory and oxidative condition exists in supporting angiogenesis deregulation and endothelial dysfunction. The use of nutraceuticals with antioxidant and anti-inflammatory activities can be a therapeutic option to maintain an adequate vascularization and endothelial cell proper functioning or to blunt aberrant angiogenesis. A revision of the updated literature reports on nutraceuticals to guide endothelial cell wellness and to restore physiological tissue vascularization is the objective of this paper. The critical aspects as well as lacking data for human use will be explored from a pharmacological perspective.

Indexed as

Dietary SupplementsAntioxidantsEndothelial CellsEye DiseasesHumansNeoplasmsNeovascularization, PathologicNeurodegenerative DiseasesOxidative StressAntioxidantsangiogenesiscancerendothelial dysfunctioninflammationnutraceuticaloxidative stress

Identifiers

PMID30340320
PMCPMC6222874
OpenAlexW2897244675

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.