Evidence map›Paper›PMID 30346541›Full record

ArticleThe Journal of clinical endocrinology and metabolism2019

Determination of Pubertal Status in Youths With Type 1 Diabetes Using Height Velocity and Trajectories.

Jia Zhu, Lisa K Volkening, Lori M Laffel

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of clinical endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jia ZhuJoslin Diabetes Center, One Joslin Place, Boston, Massachusetts.
Lisa K VolkeningJoslin Diabetes Center, One Joslin Place, Boston, Massachusetts.
Lori M LaffelJoslin Diabetes Center, One Joslin Place, Boston, Massachusetts.
Boston Children's Hospital · USJoslin Diabetes Center · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI ROHIT N. KULKARNI · 1986 to 2026
$50.5M
CAREER DEVELOPMENT IN DIABETES RESEARCH FOR PEDIATRIC ENDOCRINOLOGISTSK12DK094721 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI LAFFEL, LORI M, WHITE, MORRIS F. · 2011 to 2021
$6.3M
Optimizing CGM Use and Metabolic Outcomes in Youth with Type 1 DiabetesR01DK089349 · NIDDK · JOSLIN DIABETES CENTER · PI LAFFEL, LORI M · 2010 to 2013
$2.8M
NIDDK NIH HHS K12 DK094721NIDDK NIH HHS P30 DK036836NIDDK NIH HHS R01 DK089349
6 · The paper itself

Abstract

Context: Assessment of pubertal change is important for the management of chronic pediatric diseases, such as type 1 diabetes. Physical and/or laboratory assessments of pubertal status are often unavailable, impractical, or costly. Objective: To develop and validate a practical and objective method to assess pubertal status using longitudinal linear growth in youths with type 1 diabetes. Design, Participants, and Outcome Measurements: Participants (n = 123) were part of a 2-year study assessing continuous glucose monitoring in youths with type 1 diabetes at a tertiary diabetes center. Pubertal status at visits was assigned by a tiered approach using clinical Tanner staging or indicators of pubertal maturation from the electronic medical record when available. For other visits, independent evaluations of height velocities and growth chart trajectories provided data for pubertal status assignments. Sensitivity analysis confirmed the validity of the pubertal status assignments. Results: The sample (50% female, 95% white) had a mean ± SD age of 12.7 ± 2.7 years, diabetes duration of 6.0 ± 3.6 years, and hemoglobin A1c of 7.9 ± 0.8%. Of 985 study visits, 50% received a pubertal status assignment based on clinical Tanner staging, 29% on additional medical record review, and 22% on an evaluation of height velocity and growth chart trajectory. For the sensitivity analysis, pubertal status assignments based on height velocity and growth chart trajectory matched clinical Tanner staging in 87% of visits. Conclusions: Our practical and objective method to assess pubertal status based on height velocity and growth chart trajectory highlights growth as a reliable and objective bioassay for pubertal onset, status, and progression.

Indexed as

Body HeightGrowth ChartsPubertyAdolescentBlood GlucoseChildDiabetes Mellitus, Type 1FemaleGlycated HemoglobinGrowthHumansMaleReference StandardsSensitivity and SpecificitySexual MaturationBlood GlucoseGlycated Hemoglobin

Identifiers

PMID30346541
PMCPMC6270965
OpenAlexW2895827485

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.