Evidence mapPaperPMID 30350486Full record

ReviewThe world journal of men's health2019

Metabolic Syndrome and Male Fertility.

Ana Dias Martins, Ahmad Majzoub, Ashok Agawal

Open access · diamondAbstract readReview
In one paragraph

Review in The world journal of men's health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. The Liver-Testis Axis: Molecular Mechanisms and Clinical Implications.International journal of molecular sciences · 2026
    Review
  7. Article
  8. Metabolic syndrome in reproductive age: A cross-sectional study.International journal of reproductive biomedicine · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Ana Dias MartinsAmerican Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Cleveland, OH, USA.ORCID https://orcid.org/0000-0002-7261-9596
Ahmad MajzoubDepartment of Urology, Hamad Medical Corporation and Weill Cornell Medicine-Qatar, Doha, Qatar.ORCID https://orcid.org/0000-0001-7423-6241
Ashok AgawalAmerican Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Cleveland, OH, USA. agarwaa@ccf.org.ORCID https://orcid.org/0000-0003-0585-1026
Cleveland Clinic · USWeill Cornell Medical College in Qatar · QA

Funding

American Center for Reproductive MedicineFulbright E0585654Fundação para a Ciência e a Tecnologia SFRH/BD/108726/2015
6 · The paper itself

Abstract

Metabolic syndrome (MetS) represents a cluster of conditions that have a negative impact on human health overall. Its prevalence has been rapidly increasing worldwide and has coincided with a global decrease in birth rates and fertility potential. This review aims to address this observation through studying the relationship between MetS and male reproductive health. The effects of obesity, dyslipidemia, hypertension, and insulin resistance on male fertility were examined and supporting evidence explaining the pathophysiology of sperm dysfunction with each MetS component were described. Adopting a healthy lifestyle appears to be the single most important intervention to prevent the unwanted effects of MetS on men's health and fertility. Further studies addressing the components of MetS and their impact on male reproduction are required to enhance our understanding of the underlying pathophysiology and to propose new methods for therapeutic intervention.

Indexed as

DyslipidemiasGlucose intoleranceHypertensionInfertility, maleMetabolic syndromeObesity

Identifiers

PMID30350486
PMCPMC6479081
OpenAlexW2896897028

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.