Evidence map›Paper›PMID 30352460›Full record

ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2018

Association between Matrix Metallopeptidase 9 Polymorphism and Breast Cancer Risk.

Rogério Tadeu Felizi, Melissa Gonzalez Veiga, Ivo Carelli Filho, Ricardo Peres do Souto, César Eduardo Fernandes, Emerson Oliveira

Open access · diamondAbstract read
In one paragraph

Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rogério Tadeu FeliziDepartment of Gynecology, Faculty of Medicine of ABC, Santo André, SP, Brazil.
Melissa Gonzalez VeigaDepartment of Gynecology, Faculty of Medicine of ABC, Santo André, SP, Brazil.
Ivo Carelli FilhoDepartment of Gynecology, Faculty of Medicine of ABC, Santo André, SP, Brazil.
Ricardo Peres do SoutoDepartment of Biochemistry, Faculty of Medicine of ABC, Santo André, SP, Brazil.
César Eduardo FernandesDepartment of Gynecology, Faculty of Medicine of ABC, Santo André, SP, Brazil.
Emerson OliveiraDepartment of Gynecology, Faculty of Medicine of ABC, Santo André, SP, Brazil.
Faculdade de Medicina do ABC · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveEpidemiological studies have shown evidence of the effect of genetic variations in the pathogenesis of breast cancer and have suggested a relationship of the disease with genetic polymorphisms. Matrix metallopeptidase 9 (MMP-9) is a collagenase responsible for the degradation of type IV collagen, the major component of the basement membrane, and other essential extra cellular matrix components, being involved in the tumor cell invasion and metastasis. Our objective was to evaluate the relationship between the

methodsIn this case-control study, the frequency of the

resultsAfter adjusting for confounding variables, we found that the polymorphism was not associated with the occurrence of breast cancer (odds ratio [OR] = 1.159, 95% confidence interval [CI]: 0.6625-1.997,

conclusionWe did not observe a relationship between

Indexed as

Polymorphism, Single NucleotideBreast NeoplasmsCase-Control StudiesCross-Sectional StudiesFemaleHumansMatrix Metalloproteinase 9Middle AgedPolymorphism, GeneticRisk AssessmentMatrix Metalloproteinase 9

Identifiers

PMID30352460
PMCPMC10316932
OpenAlexW2896976884

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.