SynthesisHypertension (Dallas, Tex. : 1979)2018
Prognostic Value of Masked Uncontrolled Hypertension.
Synthesis in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of clinic and ambulatory blood pressure with new-onset atrial fibrillation: A meta-analysis of observational studies.Journal of clinical hypertension (Greenwich, Conn.) · 2021Pooled it
- Cardiovascular Events and Mortality in White Coat Hypertension: A Systematic Review and Meta-analysis.Annals of internal medicine · 2019Pooled it
- Association between high likelihood of obstructive sleep apnea and masked hypertension: findings from the Jackson heart and coronary artery risk development in young adults studies.Journal of hypertension · 2026Article
- Review
- A Narrative Review on Nitrate-Rich Diets as Adjuncts to Antihypertensive Therapy: Enhancing Treatment Efficacy via Oxidative Stress Modulation.Biomedicines · 2025Review
- Impact of Clinic Blood Pressure Target on the Prevalence and Predictors of Masked Uncontrolled Hypertension and White-Coat Uncontrolled Hypertension.Journal of Korean medical science · 2025Article
- Ambulatory blood pressure monitoring before and after resection of catecholamine-secreting pheochromocytoma or paraganglioma.Journal of human hypertension · 2025Article
- Masked uncontrolled hypertension in patients with end-stage kidney disease on in-center hemodialysis.BMC cardiovascular disorders · 2025Article
- Misclassification of Hypertension Status According to Office Blood Pressure vs 24-Hour Ambulatory Blood Pressure Monitoring.CJC open · 2025Article
- "Clinical prediction model for masked hypertension diagnosed by 24-h ambulatory blood pressure measurements in a sample from specialized hospital."Journal of human hypertension · 2025Article
- Factors Influencing Self-Care Practices and Blood Pressure Among Individuals with Uncontrolled Hypertension: A Cross-Sectional Study.Patient preference and adherence · 2025Article
- Masked uncontrolled hypertension among elderly black sub-saharan africans compared to younger adults: a cross-sectional in-hospital study.BMC cardiovascular disorders · 2024Article
- Efficacy of antihypertensive treatment for target organ protection in patients with masked hypertension (ANTI-MASK): a multicentre, double-blind, placebo-controlled trial.EClinicalMedicine · 2024Article
- The role of wearable home blood pressure monitoring in detecting out-of-office control status.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Observational
- Nocturnal systolic blood pressure dipping and progression of chronic kidney disease.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Home blood pressure measurement: the original and the best for predicting the risk.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Ambulatory Resistant Hypertension and Risk of Heart Failure in the Elderly.Diagnostics (Basel, Switzerland) · 2023Article
- Interpretation of Ambulatory Blood Pressure Monitoring for Risk Stratification in Hypertensive Patients: The 'Ambulatory Does Prediction Valid (ADPV)' Approach.Diagnostics (Basel, Switzerland) · 2023Review
- Clinical and Prognostic Value of Exaggerated Blood Pressure Response to Exercise.Reviews in cardiovascular medicine · 2023Review
- The 2022 focused update of the 2018 Korean Hypertension Society Guidelines for the management of hypertension.Clinical hypertension · 2023Review
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
The prognostic relevance of masked uncontrolled hypertension (MUCH) is incompletely clear, and its global impact on cardiovascular outcomes and mortality has not been assessed. The aim of this study was to perform a meta-analysis on the prognostic value of MUCH. We searched for articles assessing outcome in patients with MUCH compared with those with controlled hypertension (CH) and reporting adjusted hazard ratio and 95% CI. We identified 6 studies using ambulatory blood pressure monitoring (12 610 patients with 933 events) and 5 using home blood pressure measurement (17 742 patients with 394 events). The global population included 30 352 patients who experienced 1327 events. Selected studies had cardiovascular outcomes and all-cause mortality as primary outcome, and the main result is a composite of these events. The overall adjusted hazard ratio was 1.80 (95% CI, 1.57-2.06) for MUCH versus CH. Subgroup meta-analysis showed that adjusted hazard ratio was 1.83 (95% CI, 1.52-2.21) in studies using ambulatory blood pressure monitoring and 1.75 (95% CI, 1.38-2.20) in those using home blood pressure measurement. Risk was significantly higher in MUCH than in CH independently of follow-up length and types of studied events. MUCH was at significantly higher risk than CH in all ethnic groups, but the highest hazard ratio was found in studies, including black patients. Risk of cardiovascular events and all-cause mortality is significantly higher in patients with MUCH than in those with CH. MUCH detected by ambulatory or home blood pressure measurement seems to convey similar prognostic information.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.