ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2019
Active-to-Sedentary Behavior Transitions, Fatigability, and Physical Functioning in Older Adults.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
80 citing papers in PubMed, 123 citations in OpenAlex.
- Effects of Hearing Intervention on Physical Activity Measured by Accelerometry: A Secondary Analysis of the ACHIEVE Study.Journal of the American Geriatrics Society · 2025Trial
- Hearing Impairment and Physical Activity and Physical Functioning in Older Adults: Baseline Results From the ACHIEVE Trial.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Trial
- The association of vitamin D supplementation and serum vitamin D levels with physical activity in older adults: Results from a randomized trial.Journal of the American Geriatrics Society · 2023Trial
- Effects of Vibrotactile Feedback on Sedentary Behaviors in Adults: A Pilot Randomized Controlled Trial.International journal of environmental research and public health · 2019Trial
- Waking-hour movement patterns and all-cause mortality: A multi-dimensional accelerometer analysis in the UK Biobank.Journal of exercise science and fitness · 2026Article
- Accelerometry-derived activity fragmentation as a predictor of brain atrophy and disability progression in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2026Article
- Association of Changes in Activity Patterns With Brain Atrophy and Disability Progression in People With Multiple Sclerosis.Neurology · 2026Article
- Physical Activity Fragmentation and All-Cause Mortality in Hemodialysis Patients: Insights From Fitbit Study.Kidney medicine · 2026Article
- The longitudinal relation between purpose in life and accelerometer-measured physical activity.Mental health and physical activity · 2026Article
- Differences in Physical Activity Assessed by Accelerometry across Hemodialysis Days and Shifts.Clinical journal of the American Society of Nephrology : CJASN · 2026Article
- Every move counts: but some more than others.The international journal of behavioral nutrition and physical activity · 2026Article
- Does sit-to-stand transition velocity vary across the day? Association with physical functioning and fatigability in community-dwelling older adults.Innovation in aging · 2026Article
- The association of physical activity with perceived fatigability among community-dwelling older adults aged ≥60 years in regional China.Preventive medicine reports · 2025Article
- Short-term changes in objectively measured activity predict brain atrophy and disability progression in multiple sclerosis.medRxiv : the preprint server for health sciences · 2025Article
- Does accelerometer-measured physical activity and sedentary time differ between manual, in-office, hybrid and remote workers?Occupational and environmental medicine · 2025Article
- Consumer Wearable Device Measures of Gait Cadence and Activity Fragmentation as Predictors of Survival Among Patients Undergoing Chemotherapy.JCO clinical cancer informatics · 2025Observational
- Physical Activity Patterns and Variability, Cognitive Performance, and Dementia in the National Health and Aging Trends Study.Medicine and science in sports and exercise · 2025Article
- Trends and driving factors of age-related hearing loss and severity over 30 years: a cross-sectional study.BMC geriatrics · 2025Observational
- Associations Between 10-Year Physical Performance and Activities of Daily Living Trajectories and Physical Behaviors in Older Adults.International journal of environmental research and public health · 2025Article
- Using Wearable Devices to Examine the Associations of Sedentary Behavior with Perceived and Performance Fatigability Among Older Adults: The Study of Muscle, Mobility and Aging (SOMMA).Sensors (Basel, Switzerland) · 2025Article
20 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundWith aging, daily physical activity (PA) becomes less frequent and more fragmented. Accumulation patterns of daily PA-including transitions from active-to-sedentary behaviors-may provide important insights into functional status in older, less active populations.
methodsParticipants of the Baltimore Longitudinal Study of Aging (n = 680, 50% male, aged 27-94 years) completed a clinical assessment and wore an Actiheart accelerometer. Transitions between active and sedentary states were modeled as a probability (Active-to-Sedentary Transition Probability [ASTP]) defined as the reciprocal of the average PA bout duration. Cross-sectional associations between ASTP and gait speed (m/s), fatigability (rating-of-perceived-exertion [RPE]), 400 m time (seconds), and expanded short physical performance battery score were modeled using linear and logistic regression, adjusted for chronic conditions. Further analyses explored the utility of ASTP over-and-above total daily PA.
resultsIn continuous models, each 0.10-unit higher ASTP was associated slower gait (β = -0.06 m/s, SE = 0.01), higher fatigability (β = 0.60 RPE, SE = 0.12), slower 400 m time (β = 16.31 s, SE = 2.70), and lower functioning (β = -0.13 expanded short physical performance battery score, SE = 0.03; p < .001). In categorical analyses, those in the highest tertile of ASTP were >2 times more likely to have high fatigability (rating of perceived exertion ≥10), slow 400 m time (>300 seconds) and reduced functional performance (expanded short physical performance battery score < 3.07) than those in the lowest tertile (p < .01). Further analyses demonstrated ASTP provided additional insight into functional outcomes beyond total daily PA.
conclusionFragmented daily PA-as measured by ASTP-is strongly linked with measures of health and functional status and may identify those at risk of high fatigability and reduced functional performance over and above traditional PA metrics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.