Evidence map›Paper›PMID 30367153›Full record

ArticleActa pharmacologica Sinica2019

Propofol decreases the excitability of cholinergic neurons in mouse basal forebrain via GABA

Lei Chen, Zhi-Lai Yang, Juan Cheng, Ping-Ping Zhang, Le-Sha Zhang, Xue-Sheng Liu, Lie-Cheng Wang

Open access · bronzeAbstract read
In one paragraph

Article in Acta pharmacologica Sinica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

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  13. Effect of sleep deprivation on general anesthesia in rats.International journal of burns and trauma · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lei ChenDepartment of Pharmacology and Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Zhi-Lai YangDepartment of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
Juan ChengDepartment of Pharmacology and Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Ping-Ping ZhangDepartment of Pharmacology and Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Le-Sha ZhangDepartment of Pharmacology and Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China.
Xue-Sheng LiuDepartment of Anesthesiology, First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China. liu711029@hotmail.com.
Lie-Cheng WangDepartment of Pharmacology and Physiology, School of Basic Medical Sciences, Anhui Medical University, Hefei, 230032, China. wangliecheng@ahmu.edu.cn.
Anhui Medical University · CNFirst Affiliated Hospital of Anhui Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Propofol is an intravenous anesthetic that can active γ-aminobutyric acid A (GABA

Indexed as

Anesthetics, IntravenousAnimalsBasal ForebrainCholinergic NeuronsHypnotics and SedativesMice, Inbred C57BLPropofolReceptors, GABA-AAnesthetics, IntravenousHypnotics and SedativesPropofolReceptors, GABA-Aanesthesiabasal forebraincholinergic neuronsGABAA receptorspicrotoxinpropofol

Identifiers

PMID30367153
PMCPMC6786414
OpenAlexW2898238489

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.