Evidence map›Paper›PMID 30367728›Full record

ArticleBritish journal of pharmacology2019

Mitochondrial depolarization stimulates vascular repair-relevant functions of CD34

Shrinidh Joshi, Yagna P R Jarajapu

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Shrinidh JoshiDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, USA.
Yagna P R JarajapuDepartment of Pharmaceutical Sciences, College of Health Professions, North Dakota State University, Fargo, ND, USA.ORCID 0000-0002-7186-3693
North Dakota State University · US

Funding

Pilot Projects: Core DP30GM103332 · NIGMS · NORTH DAKOTA STATE UNIVERSITY · PI SIBI, MUKUND P. · 2012 to 2016
$4.9M
Targeting Mas Receptor for Diabetic Vascular Disease in Older AdultsR01AG056881 · NIA · NORTH DAKOTA STATE UNIVERSITY · PI Yagna Jarajapu · 2017 to 2026
$3.2M
NIA NIH HHS R01 AG056881NIGMS NIH HHS P30 GM103332
6 · The paper itself

Abstract

background and purposeCD34 EXPERIMENTAL APPROACH: Peripheral blood was obtained from healthy individuals (n = 63), and mononuclear cells (MNCs) were separated. MNCs were enriched for lineage negative cells, followed by isolation of CD34 KEY

resultsDiazoxide stimulated the proliferation and migration of CD34 CONCLUSION AND IMPLICATIONS: Diazoxide stimulates vascular repair-relevant functions of CD34 LINKED ARTICLES: This article is part of a themed section on Mitochondrial Pharmacology: Featured Mechanisms and Approaches for Therapy Translation. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v176.22/issuetoc.

Indexed as

Antigens, CD34Cell MovementCell ProliferationCells, CulturedCyclic GMPDiazoxideHematopoietic Stem CellsHumansMitochondriaNitric OxideReactive Oxygen SpeciesAntigens, CD34Cyclic GMPDiazoxideNitric OxideReactive Oxygen Species

Identifiers

PMID30367728
PMCPMC6887676
OpenAlexW2898574622

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.