ArticleClinical cardiology2019
Impact of gender on in-hospital outcomes in patients with Takotsubo syndrome: A nationwide analysis from 2006 to 2014.
Article in Clinical cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Prognostic factors of Takotsubo cardiomyopathy: a systematic review.ESC heart failure · 2021Pooled it
- Age- and sex-based risk stratification in takotsubo syndrome: a Japanese nationwide registry study.Frontiers in cardiovascular medicine · 2026Article
- Cardiogenic Shock Complicating Takotsubo Syndrome: Sex-Related Differences.Journal of the American Heart Association · 2024Article
- Contemporary characteristics, outcomes and novel risk score for Takotsubo cardiomyopathy: a national inpatient sample analysis.Open heart · 2024Article
- Takotsubo Syndrome in Older Men - Clinical Characteristics Differ by Sex and Age.Circulation reports · 2024Article
- Gender-specific genetic and epigenetic signatures in cardiovascular disease.Frontiers in cardiovascular medicine · 2024Review
- Estradiol-mediated small GTP-binding protein GDP dissociation stimulator induction contributes to sex differences in resilience to ferroptosis in takotsubo syndrome.Redox biology · 2023Article
- Takotsubo Syndrome: Is It Just a "Broken Heart"?Journal of community hospital internal medicine perspectives · 2023Article
- Takotsubo cardiomyopathy in orthotopic liver transplant recipients: A cohort study using multi-center pooled electronic health record data.World journal of hepatology · 2022Article
- Sex differences in acute cardiovascular care: a review and needs assessment.Cardiovascular research · 2022Review
- Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes:Frontiers in cardiovascular medicine · 2022Article
- Conventional cardiovascular risk factors associated with Takotsubo cardiomyopathy: A comprehensive review.Clinical cardiology · 2021Review
- Takotsubo Syndrome: Clinical Manifestations, Etiology and Pathogenesis.Current cardiology reviews · 2021Article
- Racial differences in takotsubo cardiomyopathy outcomes in a large nationwide sample.ESC heart failure · 2020Article
- Impact of gender on in-hospital outcomes in patients with Takotsubo syndrome: A nationwide analysis from 2006 to 2014.Clinical cardiology · 2019Article
- Reply to "racial and gender disparities among patients with Takotsubo syndrome".Clinical cardiology · 2019Article
- Racial and gender disparities among patients with Takotsubo syndrome.Clinical cardiology · 2019Article
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTakotsubo syndrome (TTS) is characterized by acute, transient systolic dysfunction of the left ventricle not attributed to coronary artery disease (CAD). HYPOTHESIS: There are differences in hospital outcomes in patients admitted with TTS based on their gender.
methodsThe National Inpatient Sample database was searched for patients admitted with a principal diagnosis of TTS from 2006 to 2014 using the ICD9-CM code 429.83. Using Pearson's χ
resultsA total of 39 662 admissions with TTS were identified, 91.7% female and 8.3% male with mean age of 66.5 and 61.6 years, respectively. The incidence of TTS increased progressively from 2006 to 2014. Female patients were more likely to have hypertension, hypothyroidism, or depression. Males were more likely to use tobacco, or have known CAD. Males had almost 4-fold higher probability of in-hospital mortality compared to females (3.7% vs 1.1%; P<0.001). Certain complications including cardiogenic shock, ventricular fibrillation/tachycardia, and acute kidney injury were more common in males.
conclusionsThere are distinct gender differences in clinical characteristics of patients admitted with TTS. Although TTS is more common in females, it is associated with higher morbidity and mortality in males.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.