Evidence map›Paper›PMID 30396232›Full record

ArticleJournal of cellular and molecular medicine2019

Bmi-1 high-expressing cells enrich cardiac stem/progenitor cells and respond to heart injury.

Yuewang Song, Mengmeng Zhao, Yuan Xie, Tingfang Zhu, Wenbin Liang, Baiming Sun, Weixin Liu, Liqun Wu, Guoping Lu, Tao-Sheng Li and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Heart-derived endogenous stem cells.Molecular biology reports · 2025
    Review
  4. Review
  5. Article
  6. Development of aInternational journal of molecular sciences · 2024
    Article
  7. Article
  8. The Vascular Niche for Adult Cardiac Progenitor Cells.Antioxidants (Basel, Switzerland) · 2022
    Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Yuewang SongDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-0567-1447
Mengmeng ZhaoDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yuan XieDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tingfang ZhuDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Wenbin LiangDepartment of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON, Canada.
Baiming SunCedars-Sinai Heart Institute, Los Angeles, California.
Weixin LiuCedars-Sinai Heart Institute, Los Angeles, California.
Liqun WuDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Guoping LuDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tao-Sheng LiDepartment of Stem Cell Biology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Tong YinThe National Research Center for Translational Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID 0000-0003-3037-7629
Yucai XieDepartment of Cardiology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shanghai Jiao Tong University · CNUniversity of California, Santa Barbara · USUniversity of Ottawa · CABengbu Medical College · CNRuijin Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bmi-1 gene is well recognized as an oncogene, but has been recently demonstrated to play a role in the self-renewal of tissue-specific stem cells. By using Bmi-1

Indexed as

AnimalsCell DifferentiationCells, CulturedGreen Fluorescent ProteinsHeart InjuriesMice, Inbred C57BLMice, TransgenicMicroscopy, ConfocalMyocardial InfarctionMyocardiumMyocytes, CardiacPolycomb Repressive Complex 1Proto-Oncogene ProteinsRNA InterferenceSide-Population CellsStem CellsBmi1 protein, mouseGreen Fluorescent ProteinsPolycomb Repressive Complex 1Proto-Oncogene ProteinsBmi-1infarctionstem/progenitor cell

Identifiers

PMID30396232
PMCPMC6307799
OpenAlexW2899799360

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.