ReviewObstetrics and gynecology clinics of North America2018
Depression During and After the Perimenopause: Impact of Hormones, Genetics, and Environmental Determinants of Disease.
Review in Obstetrics and gynecology clinics of North America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 59 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Focusing on the Menopausal Transition to Improve Mid-Life Women's Health
The Effects of a Probiotic on Emotional Processing, Cognition, and the Gut Microbiome in Perimenopausal Women
Who cites it
59 citing papers in PubMed, 6 syntheses or guidelines pooled it, 174 citations in OpenAlex.
- FIGO best practice recommendations for the mental health of women at menopausal age.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Guideline
- A meta-analysis on the incidence rate of depression in Chinese menopausal women.BMC psychiatry · 2025Pooled it
- Exercise as a therapeutic strategy for depression in menopausal women: a metaanalysis of randomized trials.Frontiers in psychiatry · 2025Pooled it
- Brazilian Guideline on Menopausal Cardiovascular Health - 2024.Arquivos brasileiros de cardiologia · 2024Guideline
- Acupuncture as an Independent or Adjuvant Management to Standard Care for Perimenopausal Depression: A Systematic Review and Meta-Analysis.Frontiers in psychiatry · 2021Pooled it
- Epidemiology of depressive disorders in people living with hypertension in Africa: a systematic review and meta-analysis.BMJ open · 2020Pooled it
- Trial
- Editorial: Menopause and mental health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- The LPC-ATX-LPA-LPAR Axis in Major Depressive Disorder: From PC/LPC Metabolism to Receptor-Active Lipid Signaling.International journal of molecular sciences · 2026Review
- Comparison of Health, Quality of Life, and Psychological and Cognitive Function Between Perimenopausal and Postmenopausal Women: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Estrogen Replacement Therapy in Ovariectomized Rats: Complementary Roles of ER and GPR30 in Alleviating Depressive-like Behavior.Current issues in molecular biology · 2026Article
- Do sex and gender matter in the pharmacological treatment of depression?Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Unravelling the Association of Physical Exercise, Quality of Life and Sleep Quality Among Chinese Perimenopausal Women.International journal of women's health · 2026Article
- Egr1 is a sex-dependent regulator of neuronal chromatin, structural plasticity, and behaviour.Nature communications · 2025Article
- Urban-rural differences in influencing factors of depressive symptoms among Chinese perimenopausal women.Scientific reports · 2025Article
- Experiences of hot flashes, urinary incontinence and mood among South Asian American women: the MASALA study.Climacteric : the journal of the International Menopause Society · 2025Observational
- Sleep misperception and associated factors among middle-aged women in Korea: a cross-sectional study.Journal of Korean biological nursing science · 2025Article
- Developing a polygenic risk score for pelvic organ prolapse: a combined risk assessment approach in Chinese women.Frontiers of medicine · 2025Article
- Perimenopausal depression: Targeting inflammation and oxidative stress (Review).Molecular medicine reports · 2025Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Vulnerability to depression is increased across the menopause transition and in the early years after the final menstrual period. Clinicians should systematically screen women in this age group; if depressive symptoms or disorder are present, treatment of depression should be initiated. Potential treatments include antidepressants for moderate to severe symptoms, psychotherapy to target psychological and interpersonal factors, and hormone therapy for women with first-onset major depressive disorder or elevated depressive symptoms and at low risk for adverse effects. Behavioral interventions can improve physical activity and sleep patterns.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.