Evidence map›Paper›PMID 30406141›Full record

ArticleBioMed research international2018

Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy.

Fumi Sato-Kaneko, Xiaodong Wang, Shiyin Yao, Tadashi Hosoya, Fitzgerald S Lao, Karen Messer, Minya Pu, Nikunj M Shukla, Howard B Cottam, Michael Chan and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 2 countries.

Fumi Sato-KanekoMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Xiaodong WangMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Shiyin YaoMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Tadashi HosoyaMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Fitzgerald S LaoMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Karen MesserDivision of Biostatistics, University of California San Diego, La Jolla 92093, USA.
Minya PuDivision of Biostatistics, University of California San Diego, La Jolla 92093, USA.
Nikunj M ShuklaMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.ORCID 0000-0002-5150-7827
Howard B CottamMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.ORCID 0000-0001-7382-0585
Michael ChanMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Dennis A CarsonMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.
Maripat CorrDepartment of Medicine, University of California San Diego, La Jolla 92093, USA.
Tomoko HayashiMoores Cancer Center, University of California San Diego, La Jolla 92093, USA.ORCID 0000-0002-9589-8348
University of California San Diego · US

Funding

NIAID NIH HHS HHSN272200900034CNIAID NIH HHS HHSN272201400051C
6 · The paper itself

Abstract

For an activating immunotherapy such as adjuvants, a compound that can prolong immune stimulation may enhance efficacy. We leveraged data from two prior high throughput screens with NF-

Indexed as

ImmunotherapyAdjuvants, ImmunologicAnimalsAntibodies, MonoclonalBenzopyransCell LineCytokinesGene Expression RegulationHumansMice, Inbred C57BLMicrotubulesMitochondriaMitogen-Activated Protein KinasesNeoplasmsNF-kappa BNitrilesAdjuvants, ImmunologicAntibodies, MonoclonalBenzopyransCytokinesMitogen-Activated Protein KinasesNF-kappa BNitrilesToll-Like Receptor 4Tubulin

Identifiers

PMID30406141
PMCPMC6199861
OpenAlexW2897073478

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.