ArticleThe Journal of biological chemistry2019
Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic β cell.
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Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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42citing papers in PubMed
5.7field-weighted citation impact, top 4% of its field
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Who cites it
42 citing papers in PubMed, 82 citations in OpenAlex.
- Stem Cell Based Regenerative Applications for the Management of Diabetes Induced Systemic Complications.Stem cell reviews and reports · 2026Review
- Organelle-specific crosstalk between calcium and redox signaling in pancreatic β-cells in physiology and type 2 diabetes.Frontiers in network physiology · 2026Review
- Intracellular Calcium Dysregulation: The Hidden Culprit in the Diabetes-Gout Nexus.Biomedicines · 2025Review
- Association of Elevated Galectin-4 Concentrations with Obesity, Diabetes, and Cardiovascular Diseases.International journal of molecular sciences · 2025Review
- Identification and mechanistic insights of ubiquitin-proteasome system and pyroptosis-related biomarkers in type 2 diabetes mellitus.World journal of diabetes · 2025Article
- Ryanodine Receptors in Islet Cell Function: Calcium Signaling, Hormone Secretion, and Diabetes.Cells · 2025Review
- Natural Antidiabetic Agents: Insights into Ericaceae-Derived Phenolics and Their Role in Metabolic and Oxidative Modulation in Diabetes.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Reciprocal rescue of Wolfram syndrome by two causative genes.EMBO reports · 2025Article
- Molecular Links and Clinical Effects of Inflammation and Metabolic Background on Ischemic Stroke: An Update Review.Journal of clinical medicine · 2024Review
- β-cell neogenesis: A rising star to rescue diabetes mellitus.Journal of advanced research · 2024Review
- Disrupted Endoplasmic Reticulum CaBiology · 2024Review
- The Ailing β-Cell in Diabetes: Insights From a Trip to the ER: The 2023 Outstanding Scientific Achievement Award Lecture.Diabetes · 2024Review
- Endoplasmic reticular stress as an emerging therapeutic target for chronic pain: a narrative review.British journal of anaesthesia · 2024Review
- Role of cytosolic and endoplasmic reticulum CaPflugers Archiv : European journal of physiology · 2024Review
- Emerging therapeutic options in the management of diabetes: recent trends, challenges and future directions.International journal of obesity (2005) · 2023Review
- Impaired intracellular CaScience signaling · 2023Article
- Review
- SERCA2 regulates proinsulin processing and processing enzyme maturation in pancreatic beta cells.Diabetologia · 2023Article
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Authors and funding
11 authors at 3 institutions in 1 country.
Wataru R YamamotoDepartments of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Robert N BoneDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Paul SohnDepartments of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Farooq SyedHerman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Christopher A ReissausHerman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Amber L MosleyDepartments of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Aruna B WijeratneDepartments of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Jason D TrueDepartments of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Xin TongDepartment of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee 37235.
Tatsuyoshi KonoDepartment of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202.
Carmella Evans-MolinaDepartments of Cellular and Integrative Physiology, Indiana University School of Medicine, Indianapolis, Indiana 46202; Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202; Departments of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202; Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana 46202; Roudebush Veterans Affairs Medical Center, Indianapolis, Indiana 46202. Electronic address: cevansmo@iu.edu.
Indiana University School of MedicineRichard L. Roudebush VA Medical Center · USVanderbilt University · US
Funding
Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4MImmunology and Infectious Diseases Training ProgramT32AI060519 · NIAID · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI MARK H KAPLAN · 2004 to 2026
$6.0MMechanisms of Beta Cell Function in Health and DiseaseR01DK093954 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EVANS-MOLINA, CARMELLA · 2011 to 2019
$3.5MBiomarkers Of Beta Cell Stress In Type 1 Diabetes (BetaMarker)UC4DK104166 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI EIZIRIK, DECIO LAKS, EVANS-MOLINA, CARMELLA · 2014 to 2014
$2.4MRegulation of Calcium Homeostasis in the Pancreatic Beta CellI01BX001733 · VA · RLR VA MEDICAL CENTER · PI Carmella Evans-Molina · 2013 to 2026
–BLRD VA I01 BX001733NIAID NIH HHS T32 AI060519NIDDK NIH HHS P30 DK097512NIDDK NIH HHS R01 DK093954NIDDK NIH HHS UC4 DK104166
Abstract
Alterations in endoplasmic reticulum (ER) calcium (Ca
Indexed as
Calcium SignalingEndoplasmic Reticulum StressAnimalsCell LineDiabetes MellitusInsulin-Secreting CellsMacrocyclic CompoundsMaleMiceMice, Mutant StrainsOxazolesRyanodine Receptor Calcium Release ChannelTunicamycinUnfolded Protein ResponseMacrocyclic CompoundsOxazolesRyanodine Receptor Calcium Release ChannelTunicamycinxestospongin Cbeta cell (B-cell)calcium signalingdiabetesendoplasmic reticulum calciumendoplasmic reticulum stress (ER stress)glucose-induced calcium oscillationsinositol 1,4,5-triphosphate (IP3) receptorinositol trisphosphate receptor (InsP3R)ryanodine receptorunfolded protein response
Identifiers
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Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.