ArticleNature communications2018
Growth factor gene IGF1 is associated with bill size in the black-bellied seedcracker Pyrenestes ostrinus.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 31 citations in OpenAlex.
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- A ROR2 coding variant is associated with craniofacial variation in domestic pigeons.Current biology : CB · 2021Article
- Complex genetic architecture of three-dimensional craniofacial shape variation in domestic pigeons.Evolution & development · 2021Article
- The influence of spatially heterogeneous anthropogenic change on bill size evolution in a coastal songbird.Evolutionary applications · 2021Article
- The Genomic Landscape of Divergence Across the Speciation Continuum in Island-Colonising Silvereyes (G3 (Bethesda, Md.) · 2020Article
- Rapid morphological divergence following a human-mediated introduction: the role of drift and directional selection.Heredity · 2020Article
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
Abstract
Pyrenestes finches are unique among birds in showing a non-sex-determined polymorphism in bill size and are considered a textbook example of disruptive selection. Morphs breed randomly with respect to bill size, and differ in diet and feeding performance relative to seed hardness. Previous breeding experiments are consistent with the polymorphism being controlled by a single genetic factor. Here, we use genome-wide pooled sequencing to explore the underlying genetic basis of bill morphology and identify a single candidate region. Targeted resequencing reveals extensive linkage disequilibrium across a 300 Kb region containing the insulin-like growth factor 1 (IGF1) gene, with a single 5-million-year-old haplotype associating with phenotypic dominance of the large-billed morph. We find no genetic similarities controlling bill size in the well-studied Darwin's finches (Geospiza). Our results show how a single genetic factor may control bill size and provide a foundation for future studies to examine this phenomenon within and among avian species.
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