Evidence map›Paper›PMID 30458808›Full record

ArticleBMC complementary and alternative medicine2018

Determination of the volatile and polyphenol constituents and the antimicrobial, antioxidant, and tyrosinase inhibitory activities of the bioactive compounds from the by-product of Rosa rugosa Thunb. var. plena Regal tea.

Guixing Ren, Peng Xue, Xiaoyan Sun, Gang Zhao

Open access · goldAbstract read
In one paragraph

Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Biological Effects ofPlants (Basel, Switzerland) · 2025
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  8. Chemical Profile and Health-Promoting Activities ofPlants (Basel, Switzerland) · 2023
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  9. Biological Activities ofMolecules (Basel, Switzerland) · 2023
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  10. Review
  11. Article
  12. RoseAP: an analytical platform for gene function ofFrontiers in plant science · 2023
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  13. Article
  14. Article
  15. Article
  16. Phytochemistry, Bioactivities and Traditional Uses ofMolecules (Basel, Switzerland) · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Evaluation ofFrontiers in plant science · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Guixing RenCollege of Pharmacy and Biological Engineering, Chengdu University, Chengdu, 610000, People's Republic of China. renguixing@cdu.edu.cn.
Peng XueSocial Risk Prediction and Management, School of Public Health and Management, Weifang Medical University, No.7166 Baotong West Street Weicheng District, Weifang, 261053, People's Republic of China.
Xiaoyan SunInstitute of Crop Sciences, Chinese Academy of Agricultural Sciences, No.80 XUEYUAN South Road, Handian District, Beijing, 100081, People's Republic of China.
Gang ZhaoKey Laboratory of Coarse Cereal Processing, Ministry of Agriculture, No.2025 Chengluo Road, Longquanyi District, Chengdu, 610106, People's Republic of China. zhaogang@cdu.edu.cn.
Chengdu University · CNInstitute of Crop Sciences · CNWeifang Medical University · CN

Funding

Ginseng Planting Resource Collection and Innovation No. 20151FDA31290
6 · The paper itself

Abstract

backgroundThe phytochemical constituents and biological activities of Rosa rugosa Thunb. var. plena Regal flower cell sap (RFCS) were investigated.

methodsVolatile constituent, such as linalool, phenylethyl alcohol, citronellol, α-bisabolol, were identified by GC-MS. The contents of hyperoside, kaempferol-3-O-rutinosid, rutin, and luteolin as well as the total flavonoid content in RFCS were determined by HPLC and HPLC-MS. The total polyphenol content was evaluated by the Folin-Ciocalteu colorimetric method. The antioxidant activities of RFCS and the standards were evaluated by DPPH and ABTS radical scavenging assays. The tyrosinase inhibitory activities of the rose samples and standard substance were determined by a spectrophotometric method. The antimicrobial effects of RFCS were evaluated in terms of minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) or minimum Fungicidal concentrations (MFCs).

resultsThe rose fraction exhibited a high content of biologically active ingredients. The total content of volatile compounds in RFCS was approximately 48.21 ± 2.76 ng/mL. The total phenolic acid content and total flavonoid content were 0.31 ± 0.01 mg/mL and 0.43 ± 0.01 mg/mL, respectively. Its IC

conclusionsDue to its rose-like aroma, phenylethyl alcohol may be combined with linalool for use as a natural skin-whitening agent and skin care additive in the and pharmaceutical industries.

Indexed as

Anti-Infective AgentsAntioxidantsBacteriaChromatography, High Pressure LiquidEnzyme InhibitorsFlowersFungiGas Chromatography-Mass SpectrometryMicrobial Sensitivity TestsMonophenol MonooxygenasePlant ExtractsPolyphenolsRosaVolatile Organic CompoundsWaste ProductsAnti-Infective AgentsAntioxidantsEnzyme InhibitorsMonophenol MonooxygenasePlant ExtractsPolyphenolsVolatile Organic CompoundsWaste ProductsAntimicrobialAntioxidantPhytochemical constituentsRFCSTyrosinase inhibitory activities

Identifiers

PMID30458808
PMCPMC6247689
OpenAlexW2900901126

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.