Evidence map›Paper›PMID 30459202›Full record

ReviewThe Biochemical journal2018

Chemical biology probes of mammalian GLUT structure and function.

Geoffrey D Holman

Abstract readReview
In one paragraph

Review in The Biochemical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Antidiabetic Effect ofScientifica · 2026
    Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. GLUT5: structure, functions, diseases and potential applications.Acta biochimica et biophysica Sinica · 2023
    Review
  10. Article
  11. Review
  12. Characterization of Dendritic Cell Metabolism by Flow Cytometry.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Erythroid glucose transport in health and disease.Pflugers Archiv : European journal of physiology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Geoffrey D HolmanDepartment of Biology and Biochemistry, University of Bath, Bath BA2 7AY, U.K. g.d.holman@bath.ac.uk.ORCID 0000-0001-7045-1358

Funding

Medical Research Council G9225018Medical Research Council MR/J003417/1
6 · The paper itself

Abstract

The structure and function of glucose transporters of the mammalian GLUT family of proteins has been studied over many decades, and the proteins have fascinated numerous research groups over this time. This interest is related to the importance of the GLUTs as archetypical membrane transport facilitators, as key limiters of the supply of glucose to cell metabolism, as targets of cell insulin and exercise signalling and of regulated membrane traffic, and as potential drug targets to combat cancer and metabolic diseases such as type 2 diabetes and obesity. This review focusses on the use of chemical biology approaches and sugar analogue probes to study these important proteins.

Indexed as

AnimalsDiabetes Mellitus, Type 2GlucoseGlucose Transport Proteins, FacilitativeHumansMammalsModels, MolecularObesityProtein BindingProtein DomainsGlucoseGlucose Transport Proteins, FacilitativeGLUT4 translocationGLUT proteinsinsulin action

Identifiers

PMID30459202
PMCPMC6243331

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.