Evidence map›Paper›PMID 30462144›Full record

ArticleBriefings in bioinformatics2020

A comprehensive review of computational prediction of genome-wide features.

Tianlei Xu, Xiaoqi Zheng, Ben Li, Peng Jin, Zhaohui Qin, Hao Wu

Open access · greenAbstract read
In one paragraph

Article in Briefings in bioinformatics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Machine and Deep Learning Methods for Predicting 3D Genome Organization.Methods in molecular biology (Clifton, N.J.) · 2025
    Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
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  11. Article
  12. Predict Epitranscriptome Targets and Regulatory Functions ofEvolutionary bioinformatics online · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Tianlei XuDepartment of Mathematics and Computer Science, Emory University, Atlanta, GA, USA.
Xiaoqi ZhengDepartment of Mathematics, Shanghai Normal University, Shanghai, China.
Ben LiDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Peng JinDepartment of Human Genetics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Zhaohui QinDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.ORCID 0000-0002-1583-146X
Hao WuDepartment of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
Emory University · USShanghai Normal University · CN

Funding

Translational models of neurodevelopmental epigenetics and disease using human iPSCsP01NS097206 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SONG, HONGJUN · 2016 to 2020
$4.3M
Statistical Methods for Single-Cell RNA-SeqR01GM122083 · NIGMS · EMORY UNIVERSITY · PI WU, HAO · 2016 to 2020
$1.7M
NIGMS NIH HHS R01 GM122083NINDS NIH HHS P01 NS097206
6 · The paper itself

Abstract

There are significant correlations among different types of genetic, genomic and epigenomic features within the genome. These correlations make the in silico feature prediction possible through statistical or machine learning models. With the accumulation of a vast amount of high-throughput data, feature prediction has gained significant interest lately, and a plethora of papers have been published in the past few years. Here we provide a comprehensive review on these published works, categorized by the prediction targets, including protein binding site, enhancer, DNA methylation, chromatin structure and gene expression. We also provide discussions on some important points and possible future directions.

Indexed as

genomic featuresmachine learningprediction model

Identifiers

PMID30462144
PMCPMC10233247
OpenAlexW2911989762

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.