Evidence map›Paper›PMID 30464301›Full record

ArticleScientific reports2018

Impact of uranium uptake on isotopic fractionation and endogenous element homeostasis in human neuron-like cells.

Eduardo Paredes, Emilie Avazeri, Véronique Malard, Claude Vidaud, Pascal E Reiller, Richard Ortega, Anthony Nonell, Hélène Isnard, Frédéric Chartier, Carole Bresson

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Uranium Isotopes: From Geosciences to Biomedical Sciences.Current environmental health reports · 2026
    Review
  2. Article
  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Eduardo ParedesDen - Service d'Etudes Analytiques et de Réactivité des Surfaces (SEARS), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France.
Emilie AvazeriCEA, DRF, Biosciences and biotechnologies institute (BIAM), F-30200, Bagnols-sur-Cèze, France.
Véronique MalardLaboratory of Protein-Metal Interactions (LIPM), Institute of Biosciences and Biotechnologies of Aix Marseille (BIAM), UMR7265 CEA - CNRS - Aix Marseille Univ, CEA Cadarache, F-13108, Cadarache, France.
Claude VidaudCEA, DRF, Biosciences and biotechnologies institute (BIAM), F-30200, Bagnols-sur-Cèze, France.
Pascal E ReillerDen - Service d'Etudes Analytiques et de Réactivité des Surfaces (SEARS), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France.
Richard OrtegaUniversity of Bordeaux, CENBG, UMR 5797, F-33170, Gradignan, France.
Anthony NonellDen - Service d'Etudes Analytiques et de Réactivité des Surfaces (SEARS), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France.
Hélène IsnardDen - Service d'Etudes Analytiques et de Réactivité des Surfaces (SEARS), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France.
Frédéric ChartierDen - Département de Physico-Chimie (DPC), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France.
Carole BressonDen - Service d'Etudes Analytiques et de Réactivité des Surfaces (SEARS), CEA, Université Paris-Saclay, F-91191, Gif sur Yvette, France. carole.bresson@cea.fr.
Commissariat à l'Énergie Atomique et aux Énergies Alternatives · FRUniversité Paris-Saclay · FRCEA Paris-Saclay · FRInstitut de Biosciences et Biotechnologies · FRUniversité de Bordeaux · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of natural uranium (U) on differentiated human neuron-like cells exposed to 1, 10, 125, and 250 µM of U for seven days was assessed. In particular, the effect of the U uptake on the homeostatic modulation of several endogenous elements (Mg, P, Mn, Fe, Zn, and Cu), the U isotopic fractionation upon its incorporation by the cells and the evolution of the intracellular Cu and Zn isotopic signatures were studied. The intracellular accumulation of U was accompanied by a preferential uptake of

Indexed as

Cell LineHomeostasisHumansMetalsNeuronsPhosphorusUraniumMetalsPhosphorusUranium

Identifiers

PMID30464301
PMCPMC6249223
OpenAlexW2900886983

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.