Evidence map›Paper›PMID 30475306›Full record

Trial reportJournal of occupational and environmental medicine2019

Cardiovascular Risk Factor Reduction in First Responders Resulting From an Individualized Lifestyle and Blood Test Program: A Randomized Controlled Trial.

Rosalynn Gill, Harold Robert Superko, Megan M McCarthy, Kepra Jack, Briana Jones, Debanjali Ghosh, Steve Richards, Joi A Gleason, Paul T Williams, Michael Dansinger

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03322046 (Heartmatters Challenge - First Responders), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03322046 completednot on this map

Heartmatters Challenge - First Responders

TypeobservationalSponsorBoston Heart DiagnosticsRan2013 to 2015Enrolled185ConditionsCardiovascular DiseasesArmsLifestyle Program
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rosalynn GillBoston Heart Diagnostics, Framingham, Massachusetts (Dr Gill, Ms Jones, Ms Ghosh, Mr Gleason, Dr Dansinger); Cholesterol, Genetics, and Heart Disease Institute, Carmel, California (Dr Superko); Heart Fit for Duty, Gilbert, Arizona (Ms McCarthy, Ms Jack); Mesa Fire Services, Mesa, Arizona (Mr Richards); Children's Hospital of Oakland, Oakland (Dr Williams), California; Tufts Medical Center, Boston, Massachusetts (Dr Dansinger).
Harold Robert Superko
Megan M McCarthy
Kepra Jack
Briana Jones
Debanjali Ghosh
Steve Richards
Joi A Gleason
Paul T Williams
Michael Dansinger

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe tested the hypothesis that a lifestyle program would improve risk factors linked to cardiovascular disease (CVD) in first responders.

methodsA 1-year cluster-randomized controlled clinical trial in 10 cities. Participants were 175 first responders, with increased waist circumference and/or low levels of large (α1) high-density lipoprotein (HDL) particles. The intervention group received personalized online tools and access to telephonic coaching sessions.

resultsAt 1 year the intervention significantly reduced body weight (P = 0.004) and waist circumference (P = 0.002), increased α1 HDL (P = 0.01), and decreased triglyceride (P = 0.005) and insulin concentrations (P = 0.03). Program adherence was associated with weight loss (P = 0.0005) and increases in α1 HDL (P = 0.03).

conclusionsIn first responders, a personalized lifestyle intervention significantly improved CVD risk factors in proportion to program adherence. Changes in large HDL particles were more sensitive indicators of lifestyle changes than HDL-cholesterol measurement. CLINICAL TRIAL REGISTRATION NUMBER: ClinicalTrials.gov: NCT03322046.

Indexed as

Emergency RespondersLife StyleAdultArizonaBostonCardiovascular DiseasesFemaleHealth PromotionHematologic TestsHumansLipoproteins, HDLMaleMiddle AgedLipoproteins, HDL

Identifiers

PMID30475306
PMCPMC6416033

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.