Evidence map›Paper›PMID 30478153›Full record

ArticleBlood advances2018

CD19-positive antibody-secreting cells provide immune memory.

C J Groves, J Carrell, R Grady, B Rajan, C A Morehouse, R Halpin, J Wang, J Wu, Y Shrestha, R Rayanki and 3 more

Open access · goldAbstract read
In one paragraph

Article in Blood advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
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  8. Review
  9. Article
  10. RNA Flow Cytometry for the Study of T Cell Metabolism.International journal of molecular sciences · 2021
    Review
  11. Serum CD4 Is Associated with the Infiltration of CD4Journal of immunology research · 2021
    Observational
  12. Article
  13. Article
  14. Mechanisms of organ transplant injury mediated by B cells and antibodies: Implications for antibody-mediated rejection.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2020
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

C J GrovesRespiratory Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, MD.
J CarrellLeidos Biomedical, Inc, National Cancer Institute, National Institutes of Health, Frederick, MD.
R GradyRespiratory Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, MD.
B RajanKite Pharma, Emeryville, CA.
C A MorehouseTranslational Medicine Research, MedImmune LLC, Gaithersburg, MD.
R HalpinTranslational Medicine Research, MedImmune LLC, Gaithersburg, MD.
J WangRespiratory Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, MD.
J WuNovartis Institutes for BioMedical Research, Cambridge, MA; and.
Y ShresthaTranslational Medicine Research, MedImmune LLC, Gaithersburg, MD.
R RayankiRespiratory Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, MD.
R KolbeckRespiratory Inflammation and Autoimmunity Research, MedImmune LLC, Gaithersburg, MD.
Y WangOncology Research, MedImmune LLC, Gaithersburg, MD.
R HerbstOncology Research, MedImmune LLC, Gaithersburg, MD.
National Institutes of Health · USNovartis (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Long-lived antibody-secreting cells (ASCs) are critical for the maintenance of humoral immunity through the continued production of antibodies specific for previously encountered pathogen or vaccine antigens. Recent reports describing humoral immune memory have suggested the importance of long-lived CD19

Indexed as

Immunologic MemoryAntibody-Producing CellsAntigensAntigens, CD19Bone Marrow CellsEnzyme-Linked Immunospot AssayGene Expression RegulationHumansImmunity, HumoralImmunoglobulinsRNA, MessengerSpleenVaccines, SyntheticAntigensAntigens, CD19ImmunoglobulinsRNA, MessengerVaccines, Synthetic

Identifiers

PMID30478153
PMCPMC6258909
OpenAlexW2902581677

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.