Evidence map›Paper›PMID 30478175›Full record

ArticleThe Journal of biological chemistry2019

A cysteine protease-like domain enhances the cytotoxic effects of the

Xenia Bogdanovic, Silvia Schneider, Nadezhda Levanova, Christophe Wirth, Christoph Trillhaase, Marcus Steinemann, Carola Hunte, Klaus Aktories, Thomas Jank

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Pathogen hijacks focal adhesion signaling by a T3SS effector CteX.Proceedings of the National Academy of Sciences of the United States of America · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Xenia BogdanovicFrom the Institute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany.
Silvia Schneiderthe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and.
Nadezhda Levanovathe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and.
Christophe WirthFrom the Institute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany.ORCID 0000-0001-8864-6508
Christoph Trillhaasethe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and.
Marcus Steinemannthe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and.
Carola HunteFrom the Institute for Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, carola.hunte@biochemie.uni-freiburg.de.
Klaus Aktoriesthe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and klaus.aktories@pharmakol.uni-freiburg.de.ORCID 0000-0002-5397-0436
Thomas Jankthe Institute for Experimental and Clinical Pharmacology and Toxicology, Faculty of Medicine, University of Freiburg, D-79104 Freiburg, Germany, and thomas.jank@pharmakol.uni-freiburg.de.
University of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The nematode mutualistic bacterium

Indexed as

Bacterial ToxinsCrystallography, X-RayCysteine ProteasesPhotorhabdusProtein DomainsBacterial ToxinsCysteine ProteasesAvrPphBbacterial toxinC58-like cysteine proteasecrystal structurecysteine proteasepapain-like proteaseproteasevirulence-associated protein toxinX-ray crystallographyYopT

Identifiers

PMID30478175
PMCPMC6341400
OpenAlexW2902592370

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.