Evidence map›Paper›PMID 30478985›Full record

ArticleInternational journal of geriatric psychiatry2019

Antipsychotic use and related factors among people with dementia aged 75 years or older in Japan: A comprehensive population-based estimation using medical and long-term care data.

Naoaki Kuroda, Shota Hamada, Nobuo Sakata, Boyoung Jeon, Katsuya Iijima, Satoru Yoshie, Tatsuro Ishizaki, Xueying Jin, Taeko Watanabe, Nanako Tamiya

Abstract read
In one paragraph

Article in International journal of geriatric psychiatry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Naoaki KurodaHealth Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.ORCID 0000-0003-0407-0228
Shota HamadaHealth Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.
Nobuo SakataResearch Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan.
Boyoung JeonDepartment of Health Services Research, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Katsuya IijimaInstitute of Gerontology, The University of Tokyo, Tokyo, Japan.
Satoru YoshieHealth Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.
Tatsuro IshizakiDepartment of Health Services Research, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Xueying JinHealth Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.
Taeko WatanabeDepartment of Health Services Research, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Nanako TamiyaHealth Services Research and Development Center, University of Tsukuba, Ibaraki, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesAntipsychotics are used to manage the behavioral and psychological symptoms of dementia (BPSD), despite their association with greater risks for mortality and cerebrovascular events. Previous studies in Japan have estimated the prevalence of antipsychotics among older adults who took antidementia drugs. Using long-term care (LTC) data, we aimed to obtain more accurate estimates of the prevalence of antipsychotics and to determine factors related to their use in older adults with dementia.

methodsMedical and LTC claims data and LTC certification data between April 2012 and September 2013 were obtained from a middle-sized suburban city. The 1-year prevalence of antipsychotic use was estimated among individuals with probable dementia aged greater than or equal to 75 years who were prescribed antidementia drugs and/or had dementia based on LTC needs certification data.

resultsOf 25 919 participants, 4865 had probable dementia and 1506 were prescribed antidementia drugs. The prevalence of antipsychotics among participants with probable dementia was 10.7%, which was lower than that in those who were prescribed antidementia drugs (16.4%). Among participants with probable dementia with LTC certification data available (N = 4419), lower cognitive function (vs mild; adjusted odds ratio 2.16, 95% confidence interval 1.63-2.86), antidementia drug use (2.27, 1.84-2.81), and institutional LTC services use (2.34, 1.85-2.97) were associated with greater odds of antipsychotic use, whereas older age (greater than or equal to 92 years) was associated with lower odds (vs less than 77 years; 0.42, 0.27-0.65).

conclusionsThese findings may be useful for estimating the burden of BPSD and for taking measures to reduce inappropriate antipsychotic prescription.

Indexed as

Drug UtilizationAgedAged, 80 and overAntipsychotic AgentsDementiaFemaleHumansInappropriate PrescribingJapanLong-Term CareMalePrevalenceAntipsychotic Agentsantipsychoticsbehavioral and psychological symptoms of dementiadementialong-term care

Identifiers

PMID30478985
PMCPMC6590349

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.