Evidence map›Paper›PMID 30483350›Full record

ReviewDrugs in context2018

The metabolic model of heart failure: the role of sodium glucose co-transporter-2 (SGLT-2) inhibition.

Muhammad Saad, Umut Gomceli, Pranav Ravi, Andrisael G Lacoste, Neil Shah, Timothy J Vittorio

Open access · goldAbstract readReview
In one paragraph

Review in Drugs in context, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 78% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Muhammad SaadDepartment of Internal Medicine, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Umut GomceliDepartment of Cardiology, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Pranav RaviDepartment of Internal Medicine, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Andrisael G LacosteDepartment of Internal Medicine, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Neil ShahDepartment of Internal Medicine, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Timothy J VittorioDepartment of Cardiology, Bronxcare Health System/Bronxcare Hospital Center, Bronx, NY, USA.
Montefiore Health System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Heart failure (HF) is one of the leading causes of hospital readmissions and health care expenditures. With a vast degree of advancements in the clinical approach and diagnosis, its management protocol is limited in terms of enhancing quality of life and prognosis. Type 2 diabetes mellitus (T2DM) is considered as one of the commonly associated comorbid conditions in the HF population. The understanding of the molecular and metabolic models of HF has led to the utilization of therapeutic goals of T2DM in improving HF-related complications. In the recent era, SGLT-2 inhibitors have shown success in decreasing cardiovascular mortality in the T2DM population. This article will help the reviewer to comprehend the pathophysiology of HF and the potential role of SGLT-2 inhibitors in the management algorithm of HF and its associated risk factors in T2DM.

Indexed as

heart failureSGLT-2 inhibitors

Identifiers

PMID30483350
PMCPMC6251384
OpenAlexW2901330196

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.