Evidence mapPaperPMID 30486233Full record

ArticleMarine drugs2018

Cytotoxic Potential of the Novel Horseshoe Crab Peptide Polyphemusin III.

Mariana B Marggraf, Pavel V Panteleev, Anna A Emelianova, Maxim I Sorokin, Ilia A Bolosov, Anton A Buzdin, Denis V Kuzmin, Tatiana V Ovchinnikova

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
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  11. Modified horseshoe crab peptides target and kill bacteria inside host cells.Cellular and molecular life sciences : CMLS · 2021
    Article
  12. Article
  13. Anti-inflammatory activities of arthropod peptides: a systematic review.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Mariana B MarggrafM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. thpcb92@mail.ru.
Pavel V PanteleevM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. alarm14@gmail.com.ORCID 0000-0001-8448-031X
Anna A EmelianovaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. annaemelyan@gmail.com.
Maxim I SorokinDepartment of Bioinformatics and Molecular Networks, Omicsway Corp., Walnut, CA 91789, USA. sorokin@oncobox.com.
Ilia A BolosovM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. b_off2@mail.ru.
Anton A BuzdinM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. buzdin@oncobox.com.
Denis V KuzminM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. denisk@list.ru.
Tatiana V OvchinnikovaM.M. Shemyakin & Yu.A. Ovchinnikov Institute of Bioorganic Chemistry, the Russian Academy of Sciences, Mikhluho-Maklaya str. 16/10, Moscow 117997, Russia. ovch@ibch.ru.ORCID 0000-0002-5950-249X
Institute of Bioorganic Chemistry · RUSechenov University · RU

Funding

Russian Science Foundation 14-50-00131
6 · The paper itself

Abstract

Biological activity of the new antimicrobial peptide polyphemusin III from the horseshoe crab

Indexed as

A549 CellsAnimalsAnti-Bacterial AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsApoptosisAstrocytesBacteriaCell MembraneDrug Screening Assays, AntitumorHEK293 CellsHeLa CellsHL-60 CellsHorseshoe CrabsHumansInhibitory Concentration 50Anti-Bacterial AgentsAntimicrobial Cationic PeptidesAntineoplastic AgentsRecombinant Proteinsantimicrobial peptidecell deathcytotoxicitypolyphemusinssignaling pathwaystachyplesinsβ-hairpin

Identifiers

PMID30486233
PMCPMC6315362
OpenAlexW2902345266

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.