Evidence map›Paper›PMID 30487205›Full record

Observational studyThe European respiratory journal2019

Post-approval upper airway stimulation predictors of treatment effectiveness in the ADHERE registry.

Clemens Heiser, Armin Steffen, Maurits Boon, Benedikt Hofauer, Karl Doghramji, Joachim T Maurer, J Ulrich Sommer, Ryan Soose, Patrick J Strollo, Richard Schwab and 11 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in The European respiratory journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Pooled it
  2. Trial
  3. Bilateral hypoglossal nerve stimulation for obstructive sleep apnea: a nonrandomized clinical trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Trial
  4. Relation between arousability and outcome of upper airway stimulation in the Stimulation for Apnea Reduction (STAR) Trial.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Impact of Postoperative Weight Changes on Hypoglossal Nerve Stimulation Success for Obstructive Sleep Apnea.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. How we measure hypoglossal nerve stimulator outcome matters: titration vs single amplitude efficacy sleep studies.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  18. Article
  19. The impact of neck circumference on hypoglossal nerve stimulator therapy outcomes.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article
  20. COJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Clemens HeiserDept of Otorhinolaryngology, Head and Neck Surgery, Munich Technical University, Munich, Germany.
Armin SteffenDept of Otorhinolaryngology, University of Lubeck, Lubeck, Germany.
Maurits BoonDept of Otorhinolaryngology - Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Benedikt HofauerDept of Otorhinolaryngology, Head and Neck Surgery, Munich Technical University, Munich, Germany.
Karl DoghramjiDept of Otorhinolaryngology - Head and Neck Surgery, Thomas Jefferson University, Philadelphia, PA, USA.
Joachim T MaurerDept of Otorhinolaryngology, Head and Neck Surgery, HELIOS University Hospital Wuppertal, Wuppertal, Germany.
J Ulrich SommerDept of Otorhinolaryngology, Head and Neck Surgery, HELIOS University Hospital Wuppertal, Wuppertal, Germany.
Ryan SooseDept of Otorhinolaryngology, University of Pittsburgh, Pittsburgh, PA, USA.
Patrick J StrolloDept of Otorhinolaryngology, University of Pittsburgh, Pittsburgh, PA, USA.
Richard SchwabDept of Sleep Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Erica ThalerDept of Sleep Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Kirk WithrowDept of Otorhinolaryngology, University of Alabama, Birmingham, AL, USA.
Alan KominskyDept of Otorhinolaryngology, Cleveland Clinic, Cleveland, OH, USA.
Christopher LarsenDept of Otorhinolaryngology - Head and Neck Surgery, Kansas University Medical Center, Kansas City, KS, USA.
Eric J KezirianDept of Otorhinolaryngology - Head and Neck Surgery, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
Jennifer HsiaDept of Otorhinolaryngology - Head and Neck Surgery, University of Minnesota Fairview Hospital, Minneapolis, MN, USA.
Stanley ChiaDept of Otorhinolaryngology, MedStar Washington Hospital Center, Washington, DC, USA.
John HarwickDept of Otorhinolaryngology - Head and Neck Surgery, University of Florida, Gainesville, FL, USA.
Kingman StrohlDept of Pulmonary and Critical Care Medicine and Sleep Medicine, University Hospital Cleveland Medical Center, Cleveland, OH, USA.
Reena MehraDept of Otorhinolaryngology, Cleveland Clinic, Cleveland, OH, USA.
ADHERE registry investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upper airway stimulation (UAS) has been shown to reduce severity of obstructive sleep apnoea. The aim of this study was to identify predictors of UAS therapy response in an international multicentre registry.Patients who underwent UAS implantation in the United States and Germany were enrolled in an observational registry. Data collected included patient characteristics, apnoea/hypopnoea index (AHI), Epworth sleepiness scale (ESS), objective adherence, adverse events and patient satisfaction measures.

Indexed as

Implantable NeurostimulatorsPatient SatisfactionProduct Surveillance, PostmarketingAgedElectric Stimulation TherapyFemaleGermanyHumansLogistic ModelsMaleMiddle AgedRegistriesSleep Apnea, ObstructiveTime FactorsTreatment OutcomeUnited States

Identifiers

PMID30487205
PMCPMC6319796

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.