Evidence map›Paper›PMID 30487278›Full record

ArticleJournal of virology2019

Identification and Functional Characterization of a Novel Fc Gamma-Binding Glycoprotein in Rhesus Cytomegalovirus.

Philipp Kolb, Steven Sijmons, Matthew R McArdle, Husam Taher, Jennie Womack, Colette Hughes, Abigail Ventura, Michael A Jarvis, Christiane Stahl-Hennig, Scott Hansen and 4 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
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  3. Article
  4. Evolution of theVirus evolution · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Philipp Kolb *Institute of Virology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Steven Sijmons *Vaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Matthew R McArdleVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Husam TaherVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Jennie WomackVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Colette HughesVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Abigail VenturaVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Michael A JarvisVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Christiane Stahl-HennigGerman Primate Center Göttingen, Göttingen, Germany.
Scott HansenVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Louis J PickerVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Daniel MalouliVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA.
Hartmut HengelInstitute of Virology, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Klaus FrühVaccine and Gene Therapy Institute, Oregon Health and Science University, Beaverton, Oregon, USA fruehk@ohsu.edu.
Oregon Health & Science University · USUniversity of Freiburg · DEGerman Primate Center · DE

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Virology CoreP01AI129859 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI Sallie R. Permar · 2019 to 2026
$31.0M
Virology and Vector Production Core CU19AI128741 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI KAHL, CHRISTOPH ADRIAN · 2017 to 2021
$11.8M
Evasion of Antigen Presentation by Rhesus CytomegalovirusR01AI059457 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI FRUH, KLAUS J · 2005 to 2021
$6.2M
Evasion of Antigen Presentation by Rhesus CytomegalovirusR56AI059457 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI FRUH, KLAUS J · 2016 to 2016
$567k
NIAID NIH HHS P01 AI129859NIAID NIH HHS R01 AI059457NIAID NIH HHS R56 AI059457NIAID NIH HHS U19 AI128741NIH HHS P51 OD011092
6 · The paper itself

Abstract

Receptors recognizing the Fc part of immunoglobulin G (FcγRs) are key determinants in antibody-mediated immune responses. Members of the

Indexed as

AnimalsAntibodies, ViralCarrier ProteinsCell LineCytomegalovirusCytomegalovirus InfectionsGlycoproteinsHEK293 CellsHeLa CellsHumansImmunoglobulin GMacaca mulattaMiceProtein BindingReceptors, IgGSignal TransductionAntibodies, ViralCarrier ProteinsGlycoproteinsImmunoglobulin GReceptors, IgGViral Proteinsantibody functioncytomegalovirusFc receptorsimmune evasionimmunologyrhesusvirology

Identifiers

PMID30487278
PMCPMC6364020
OpenAlexW2902655641

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.