Evidence map›Paper›PMID 30513330›Full record

ArticleCurrent biology : CB2018

Cell Cycle: Abrogating Interphase/M Phase Bistability.

Michael L Goldberg

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Current biology : CB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael L GoldbergDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853-2703, USA. Electronic address: mlg11@cornell.edu.
Cornell University · US

Funding

Greatwall Kinase and the Mitotic Control of Phosphatase ActivityR01GM048430 · NIGMS · CORNELL UNIVERSITY ITHACA · PI GOLDBERG, MICHAEL L · 1992 to 2017
$6.6M
NIGMS NIH HHS R01 GM048430
6 · The paper itself

Abstract

A new study reports the ability to generate cells caught in a 'no-man's land' between interphase and M phase by simultaneously disrupting feedback loops controlling the activities of the main mitotic driver Cdk1-cyclin B and its counteracting phosphatase PP2A-B55.

Indexed as

MitosisProtein Phosphatase 2AnimalsCDC2 Protein KinaseInterphasePhosphorylationCDC2 Protein KinaseProtein Phosphatase 2

Identifiers

PMID30513330
OpenAlexW2903349962

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.